1. Gene
  2. Ntf5 - neurotrophin 5 Gene

Ntf5 - neurotrophin 5 Gene

种属: Mus musculus

同用名: NT4; NT-4; NT-5; Ntf4; NT4/5; Ntf-5; 2900040K06Rik

基因 ID: 78405 | 基因类型: protein coding

关于 Ntf5

功能概要

This gene encodes a secreted protein belonging to the neurotrophin family of structurally related molecules that play a crucial role in the control of neuronal numbers and of dendritic growth. The encoded preproprotein undergoes post-translational processing to generate non-covalently associated homodimeric functional protein. Mice deficient in the encoded protein exhibit a loss of sensory neurons in the nodose-petrosal and geniculate ganglia, have deficits in long-term memory and hippocampal long-lasting long-term potentiation. [provided by RefSeq, Oct 2015]

Ntf5 基因产物(1)

mRNA Protein Name
NM_198190.1 NP_937833.1 neurotrophin-4 preproprotein
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within adult locomotory behavior IMP
IMP: 通过突变表型推断
10681461 MGI
involved in ameloblast differentiation IMP
IMP: 通过突变表型推断
27015268 MGI
acts upstream of or within epidermis development IMP
IMP: 通过突变表型推断
9973328 MGI
acts upstream of or within ganglion mother cell fate determination IMP
IMP: 通过突变表型推断
10681461 MGI
acts upstream of or within innervation IDA
IDA: 通过直接分析推断
24378336 MGI
acts upstream of or within long-term memory IMP
IMP: 通过突变表型推断
10869436 MGI
acts upstream of or within mechanoreceptor differentiation IGI
IGI: 通过遗传相互作用推断
15376326 MGI
acts upstream of or within negative regulation of programmed cell death IDA
IDA: 通过直接分析推断
24378336 MGI
acts upstream of or within sensory organ boundary specification IMP
IMP: 通过突变表型推断
10479455 MGI
acts upstream of or within taste bud development IDA
IDA: 通过直接分析推断
24378336 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

neurotrophin-4

neutrophic factor 4

重组 Ntf5 蛋白

目录号 产品名 蛋白编号 纯度
HY-P7273 NT-4 Protein, Mouse Q80VU4 (G80-A209) ≥95%