CUEDC2 - CUE domain containing 2 Gene

中文名称：含 CUE 域 2

种属: Homo sapiens

同用名: C10orf66; bA18I14.5

基因 ID: 79004 | 基因类型: protein coding

关于 CUEDC2

Cytogenetic location: 10q24.32 Genomic coordinates (GRCh38): 10:102,423,249-102,432,574 (from NCBI)

This gene has 4 transcripts (splice variants) and 189 orthologues. Ubiquitous expression in brain (RPKM 31.2), heart (RPKM 24.6) and 25 other tissues.

功能概要

预测启用泛素结合活性。在参与炎症反应的细胞因子产生的负调节和巨噬细胞细胞因子产生的负调节中发挥作用。位于胞质溶胶中；核膜;和核质。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable ubiquitin binding activity. Acts upstream of or within negative regulation of cytokine production involved in inflammatory response and negative regulation of macrophage cytokine production. Located in cytosol; nuclear membrane; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

CUEDC2 基因产物(1)

mRNA	Protein	Name
NM_024040.3	NP_076945.2	CUE domain-containing protein 2

基因本体论

分子功能
生物过程

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	17347654	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
acts upstream of or within negative regulation of cytokine production involved in inflammatory response	IMP IMP: 通过突变表型推断	24882011	GOA
acts upstream of or within negative regulation of macrophage cytokine production	IMP IMP: 通过突变表型推断	24882011	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

CUEDC2 蛋白结构

CUE

0
100
200
287 a.a.

蛋白主名

其他名称

CUE domain-containing protein 2

CUEDC2 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	CUEDC2	Q9H467	ESR1	Homo sapiens	P03372	Pull Down	17347654
种属内	CUEDC2	Q9H467	PGR	Homo sapiens	P06401	Confocal	17347654
种属内	CUEDC2	Q9H467	PGR	Homo sapiens	P06401	Anti Tag CoIP	17347654
种属内	CUEDC2	Q9H467	PGR	Homo sapiens	P06401	Pull Down	17347654

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Hypertrophy Of Breast

Breasts Enlarged	Large Breast
Hypertrophy Of Breast Nos	Hypertrophy Of Male Breast
Hypertrophic Breast	Excessive Development Of Breast
Macromastia	Mastoplastia

Myasthenic Syndrome, Congenital, 5

Endplate Acetylcholinesterase Deficiency	Congenital Myasthenic Syndrome 5
CMS5	Ead
Engel Congenital Myasthenic Syndrome	Myasthenic Syndrome, Congenital, Engel Type
Cms Ic	Congenital Myasthenic Syndrome Type Ic
Congenital Myasthenic Syndrome Type Ic, Formerly	Cms1c, Formerly
Cms Ic, Formerly	Congenital Myasthenic Syndrome Engel Type
End Plate Acetylcholinesterase Deficiency	Synaptic Congenital Myasthenic Syndromes
Cms1c	Cmse
Congenital Myasthenic Syndrome Type 1c	End-Plate Acetylcholinesterase Deficiency
Myasthenic Syndrome, Congenital, Type 5

Breast Cancer

Breast Carcinoma	Male Breast Cancer
Breast Cancer, Familial	Malignant Neoplasm Of Breast
Breast Cancer, Susceptibility To	Breast Cancer, Early-Onset
Malignant Tumor Of Breast	Carcinoma Of Male Breast
Breast Cancer, Invasive Ductal	Breast Cancer, Protection Against
Breast Cancer, Somatic	Breast Cancer, Male
Breast Cancer, Lobular, Somatic	Breast Tumor
Mammary Cancer	Mammary Tumor
Malignant Neoplasm Of Male Breast	Mammary Carcinoma
Male Breast Carcinoma	Familial Cancer Of Breast
Invasive Ductal Breast Carcinoma	Breast Cancer Susceptibility
Breast Cancer, Male, Susceptibility To	Breast Cancer, Early-Onset, Susceptibility To
Malignant Tumor Of The Breast	Mammary Neoplasm
Primary Breast Cancer	Neoplasm Of Male Breast
Carcinoma Of Breast	Breast Cancer In Men
Familial Breast Cancer	Cancer Of Breast
BC	Breast Cancer Familial
Breast Cancer Familial Male	Breast Cancer, Familial Male
Breast Male Carcinoma	Breast Neoplasms
Breast Neoplasms, Male	Mammary Tumors
Mammary Carcinomas	Cancer, Breast
Cancer, Breast, Susceptibility	Invasive Breast Ductal Carcinoma
Breast Neoplasm	Susceptibility To Breast Cancer
Mammary Neoplasms	Animal Mammary Neoplasms
Primary Malignant Neoplasm Of Breast	Infiltrating Ductal Carcinoma Of Breast
Infiltrating Duct Carcinoma Of Unspecified Site	Infiltrating Ductular Carcinoma Of Unspecified Site
Invasive Breast Carcinoma Of No Special Type	Microinvasive Carcinoma Of Breast
Carcinoma With Apocrine Differentiation

Autism

Autistic Disorder	Autism Susceptibility 1
Childhood Autism	Autistic Disorder Of Childhood Onset
Infantile Autism	Kanner'S Syndrome
Autistic

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS03358	CUEDC2 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Mus musculus	CUEDC2	MGD	MGI:1914366
Felis catus	CUEDC2	VGNC	VGNC:61281
Bos taurus	CUEDC2	VGNC	VGNC:55945
Canis familiaris	CUEDC2	VGNC	VGNC:39727
Rattus norvegicus	CUEDC2	RGD	RGD:1308096

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

CUEDC2 - CUE domain containing 2 Gene

关于 CUEDC2

功能概要

CUEDC2 基因产物(1)

CUEDC2 蛋白结构

CUEDC2 蛋白互作信息

关联疾病

直系同源

热门区域

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CUEDC2 - CUE domain containing 2 Gene

关于 CUEDC2

功能概要

CUEDC2 基因产物(1)

CUEDC2 蛋白结构

CUEDC2 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z