1. Gene
  2. GID4 - GID complex subunit 4 homolog Gene

GID4 - GID complex subunit 4 homolog Gene

中文名称:GID 复杂亚基 4 同系物

种属: Homo sapiens

同用名: VID2; VID24; C17orf39

基因 ID: 79018 | 基因类型: protein coding

关于 GID4

Cytogenetic location: 17p11.2 Genomic coordinates (GRCh38): 17:18,039,408-18,068,405 (from NCBI)

This gene has 5 transcripts (splice variants) and 260 orthologues. Broad expression in testis (RPKM 9.8), esophagus (RPKM 5.1) and 25 other tissues.

功能概要

多蛋白介质复合物是 DNA 结合转录因子激活 RNA 聚合酶 II 转录所需的共激活因子。该基因编码的蛋白质被认为是介体复合体的一个亚基。该基因位于 17 号染色体上的 Smith-Magenis 综合征区域内。[RefSeq 提供,2008 年 7 月]

The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith-Magenis syndrome region on chromosome 17. [provided by RefSeq, Jul 2008]

GID4 基因产物(2)

mRNA Protein Name
NM_001411057.1 NP_001397986.1 glucose-induced degradation protein 4 homolog isoform 2
NM_024052.5 NP_076957.3 glucose-induced degradation protein 4 homolog isoform 1
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of ubiquitin ligase complex IDA
IDA: 通过直接分析推断
29911972 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

GID4 蛋白结构

Vac_ImportDeg

Vac_ImportDeg: Vacuolar import and degradation protein (121 - 289)

  • 0
  • 100
  • 200
  • 300 a.a.
蛋白主名 其他名称

glucose-induced degradation protein 4 homolog

GID complex subunit 4, VID24 homolog

关联疾病

疾病名称 别名
Smith-Magenis Syndrome

SMS

Chromosome 17p11.2 Deletion Syndrome

17p11.2 Microdeletion Syndrome

17p11.2 Monosomy

Chromosome 17p Deletion Syndrome

Del(17)

P11.2

17p- Syndrome

Deletion 17p Syndrome

Partial Monosomy 17p

Malignant Giant Cell Tumor

Malignant Tumor, Giant Cell Type

Malignant Giant Cell Neoplasm

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Mus musculus GID4 MGD MGI:1914021
Macaca mulatta GID4 VGNC VGNC:104604
Rattus norvegicus GID4 RGD RGD:1588894
Bos taurus GID4 VGNC VGNC:55833
Canis familiaris GID4 VGNC VGNC:49858
Felis catus GID4 VGNC VGNC:62549