2. Gene
  3. FSD1 - fibronectin type III and SPRY domain containing 1 Gene

FSD1 - fibronectin type III and SPRY domain containing 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：含纤连蛋白 III 型和 SPRY 域 1

种属: Homo sapiens

同用名: MIR1; GLFND

基因 ID: 79187 | 基因类型: protein coding

关于 FSD1

Cytogenetic location: 19p13.3 Genomic coordinates (GRCh38): 19:4,304,598-4,323,836 (from NCBI)

This gene has 10 transcripts (splice variants), 197 orthologues and 3 paralogues. Biased expression in brain (RPKM 10.1), testis (RPKM 4.8) and 2 other tissues.

功能概要

该基因编码一种中心体相关蛋白，其特征在于 B-box (BBC) 结构域下游的 N 末端卷曲螺旋区域、中心纤连蛋白 III 型结构域以及 splA 和 RyR (SPRY) 结构域中的 C 末端重复序列.编码的蛋白质与微管的一个子集相关联，并且可能参与胞质分裂过程中微管的稳定性和组织。[RefSeq 提供，2009 年 4 月]

This gene encodes a centrosome associated protein that is characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III domain, and a C-terminal repeats in splA and RyR (SPRY) domain. The encoded protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis. [provided by RefSeq, Apr 2009]

FSD1 基因产物(2)

mRNA Protein Name
NM_001330429.2 NP_001317358.1 fibronectin type III and SPRY domain-containing protein 1 isoform 2
NM_024333.3 NP_077309.1 fibronectin type III and SPRY domain-containing protein 1 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables identical protein binding IPI
IPI: 通过物理相互作用推断
12154070 GOA
enables microtubule binding IMP
IMP: 通过突变表型推断
12154070 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cytoplasmic microtubule organization IMP
IMP: 通过突变表型推断
12154070 GOA
involved in regulation of cell division IDA
IDA: 通过直接分析推断
12445389 GOA
involved in regulation of cytokinesis IDA
IDA: 通过直接分析推断
12445389 GOA
involved in regulation of mitotic spindle organization IDA
IDA: 通过直接分析推断
12154070 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in centrosome IMP
IMP: 通过突变表型推断
12154070 GOA
located in microtubule IMP
IMP: 通过突变表型推断
12154070 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

fibronectin type III and SPRY domain-containing protein 1

MID1-related protein 1

关联疾病

疾病名称 别名
Mitochondrial Dna Depletion Syndrome 12a
Spastic Paraplegia 16, X-Linked

SPG16

Hereditary Spastic Paraplegia 16

X-Linked Spastic Paraplegia Type 16

Spastic Paraplegia 16, X-Linked, Complicated

X-Linked Spastic Paraplegia 16

Spastic Paraplegia 16

Spastic Paraplegia-16, X-Linked, Complicated
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05121 FSD1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus FSD1 VGNC VGNC:62375
Rattus norvegicus FSD1 RGD RGD:1583850
Canis familiaris FSD1 VGNC VGNC:40993
Bos taurus FSD1 VGNC VGNC:29129
Mus musculus FSD1 MGD MGI:1934858
Macaca mulatta FSD1 VGNC VGNC:72718
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