2. Gene
  3. Lias - lipoic acid synthetase Gene

Lias - lipoic acid synthetase Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: LS; 7a5ex; lip-syn; 2900022L22Rik; 4933425M12Rik

基因 ID: 79464 | 基因类型: protein coding

关于 Lias

功能概要

Enables lipoate synthase activity. Acts upstream of or within several processes, including lipoate biosynthetic process; neural tube closure; and response to lipopolysaccharide. Located in mitochondrion. Is expressed in alimentary system; liver; metanephros; salivary gland; and urinary system. Human ortholog(s) of this gene implicated in pyruvate decarboxylase deficiency. Orthologous to human LIAS (lipoic acid synthetase). [provided by Alliance of Genome Resources, Apr 2022]

Lias 基因产物(2)

mRNA Protein Name
NM_001310612.1 NP_001297541.1 lipoyl synthase, mitochondrial isoform 2
NM_024471.5 NP_077791.1 lipoyl synthase, mitochondrial isoform 1 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables lipoate synthase activity IGI
IGI: 通过遗传相互作用推断
11389890 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within inflammatory response IMP
IMP: 通过突变表型推断
18845616 MGI
acts upstream of or within lipoate biosynthetic process IGI
IGI: 通过遗传相互作用推断
11389890 MGI
acts upstream of or within neural tube closure IMP
IMP: 通过突变表型推断
15755804 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: 通过突变表型推断
18845616 MGI
acts upstream of or within response to oxidative stress IMP
IMP: 通过突变表型推断
18845616 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
11389890 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

lipoyl synthase, mitochondrial

lipoate synthase

lipoic acid synthase

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS07639 LIAS Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS16259 Lias Mouse Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Lias NCBI NCBI:11019
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