ARHGAP10 - Rho GTPase activating protein 10 Gene

中文名称：Rho GTP 酶激活蛋白 10

种属: Homo sapiens

同用名: GRAF2; PSGAP; PS-GAP

基因 ID: 79658 | 基因类型: protein coding

关于 ARHGAP10

Cytogenetic location: 4q31.23 Genomic coordinates (GRCh38): 4:147,732,088-148,072,776 (from NCBI)

This gene has 7 transcripts (splice variants), 211 orthologues and 3 paralogues. Ubiquitous expression in esophagus (RPKM 17.3), ovary (RPKM 10.9) and 23 other tissues.

功能概要

预测启用 GTPase 激活剂活动。预计参与细胞骨架组织和细胞凋亡过程的负调控。预测位于细胞质和质膜的核周区。预计在胞质溶胶中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable GTPase activator activity. Predicted to be involved in Cytoskeleton organization and negative regulation of apoptotic process. Predicted to be located in perinuclear region of cytoplasm and plasma membrane. Predicted to be active in cytosol. [provided by Alliance of Genome Resources, Apr 2022]

ARHGAP10 基因产物(1)

mRNA	Protein	Name
NM_024605.4	NP_078881.3	rho GTPase-activating protein 10

基因本体论

分子功能
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	11432776	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in cytosol	IDA IDA: 通过直接分析推断	32344433	GOA
located in endosome membrane	IDA IDA: 通过直接分析推断	32344433	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ARHGAP10 蛋白结构

RhoGAP

SH3_9

0
200
400
600
786 a.a.

蛋白主名

其他名称

rho GTPase-activating protein 10

GTPase regulator associated with focal adhesion kinase 2

关联疾病

疾病名称

别名

Urocanase Deficiency

Encephalopathy Due To Urocanase Deficiency	Urocanate Hydratase Deficiency
Urocanic Aciduria	UROCD
High Urine Urocanic Acid Levels

Aarskog-Scott Syndrome

Aarskog Syndrome	Faciogenital Dysplasia
Faciodigitogenital Syndrome	AAS
Fgdy	X-Linked Aarskog Syndrome
Intellectual Developmental Disorder, X-Linked, Syndromic 16	Aarskog Syndrome, X-Linked
Intellectual Developmental Disorder, X-Linked Syndromic 16	Greig'S Syndrome
Aarskog Scott Syndrome	Aarskog Disease
Scott Aarskog Syndrome	Facio-Digito-Genital Dysplasia
Faciogenital Dysplasia With Attention Deficit-Hyperactivity Disorder	Aarskog-Scott Syndrome ) Syndrome

Non-Syndromic X-Linked Intellectual Disability 30

Mrx30	Mrx47
X-Linked Mental Retardation 30/47	X-Linked Mental Retardation 47
Mental Retardation, X-Linked, Type 30/47

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式 Pre-designed Sets	纯度	是否罕见病否
HY-RS00912	ARHGAP10 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Macaca mulatta	ARHGAP10	VGNC	VGNC:69914
Felis catus	ARHGAP10	VGNC	VGNC:59874
Rattus norvegicus	ARHGAP10	RGD	RGD:1588859
Canis familiaris	ARHGAP10	VGNC	VGNC:38045
Mus musculus	ARHGAP10	MGD	MGI:1925764
Bos taurus	ARHGAP10	VGNC	VGNC:26074

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

ARHGAP10 - Rho GTPase activating protein 10 Gene

关于 ARHGAP10

功能概要

ARHGAP10 基因产物(1)

ARHGAP10 蛋白结构

关联疾病

直系同源

热门区域

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ARHGAP10 - Rho GTPase activating protein 10 Gene

关于 ARHGAP10

功能概要

ARHGAP10 基因产物(1)

ARHGAP10 蛋白结构

关联疾病

相关产品

直系同源

热门区域

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B

C

F

G

H

J

L

N

Q

S

T

X

Y

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