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  2. MICALL2 - MICAL like 2 Gene

MICALL2 - MICAL like 2 Gene

中文名称:MICAL 样 2

种属: Homo sapiens

同用名: JRAB; MICAL-L2

基因 ID: 79778 | 基因类型: protein coding

关于 MICALL2

This gene has 15 transcripts (splice variants), 255 orthologues and 7 paralogues. Broad expression in spleen (RPKM 13.4), small intestine (RPKM 10.9) and 23 other tissues.

功能概要

启用细丝蛋白结合活性。参与蛋白质靶向线粒体的正调节。预计位于多个细胞成分中,包括双细胞紧密连接;神经元投射;和回收核内体。预测与应力纤维共定位。 [由基因组资源联盟提供,2022 年 4 月]

Enables filamin binding activity. Involved in positive regulation of protein targeting to mitochondrion. Predicted to be located in several cellular components, including bicellular tight junction; neuron projection; and recycling endosome. Predicted to colocalize with stress fiber. [provided by Alliance of Genome Resources, Apr 2022]

MICALL2 基因产物(1)

mRNA Protein Name
NM_182924.4 NP_891554.1 MICAL-like protein 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables filamin binding IDA
IDA: 通过直接分析推断
23890175 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

MICALL2 蛋白结构

CH

CH: Calponin homology (CH) domain (6 - 106)

LIM

LIM: LIM domain (188 - 241)

DUF3585

DUF3585: Protein of unknown function (DUF3585) (736 - 872)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 904 a.a.
蛋白主名 其他名称

MICAL-like protein 2

junctional Rab13-binding protein

MICALL2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
MICALL2 Q8IY33 DCDC2 Homo sapiens Q9UHG0 32296183
种属内
MICALL2 Q8IY33 DCDC2 Homo sapiens Q9UHG0 32296183
种属内
MICALL2 Q8IY33 DCDC2 Homo sapiens Q9UHG0 32296183
种属内
MICALL2 Q8IY33 CDR2 Homo sapiens Q01850 32296183
种属内
MICALL2 Q8IY33 CDR2 Homo sapiens Q01850 32296183
种属内
MICALL2 Q8IY33 CDR2 Homo sapiens Q01850 32296183
种属内
MICALL2 Q8IY33 ACTN3 Homo sapiens Q08043 32296183
种属内
MICALL2 Q8IY33 ACTN3 Homo sapiens Q08043 32296183
种属内
MICALL2 Q8IY33 ACTN4 Homo sapiens O43707 32296183
种属内
MICALL2 Q8IY33 ACTN4 Homo sapiens O43707 32296183
种属内
MICALL2 Q8IY33 ACTN1 Homo sapiens P12814 32296183
种属内
MICALL2 Q8IY33 ACTN1 Homo sapiens P12814 25416956
种属内
MICALL2 Q8IY33 ACTN1 Homo sapiens P12814 32296183
种属内
MICALL2 Q8IY33 ACTN1 Homo sapiens P12814 25416956
种属内
MICALL2 Q8IY33 ACTN2 Homo sapiens P35609 31515488
种属内
MICALL2 Q8IY33 ACTN2 Homo sapiens P35609 25416956
种属内
MICALL2 Q8IY33 ACTN2 Homo sapiens P35609 32296183
种属内
MICALL2 Q8IY33 ACTN2 Homo sapiens P35609 32296183
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Joubert Syndrome 1

Joubert Syndrome

Jbts

Cerebellooculorenal Syndrome 1

JBTS1

Joubert-Boltshauser Syndrome

Cerebelloparenchymal Disorder Iv

Cpd4

Cors1

Joubert Syndrome And Related Disorders

Jsrd

Familial Aplasia Of The Vermis

Joubert Syndrome Related Disorders

Js

Cerebellar Vermis Agenesis

Cerebelloparenchymal Disorder 4

Agenesis Of Cerebellar Vermis

Cerebello-Oculo-Renal Syndrome

Cors

Joubert-Bolthauser Syndrome

Cpd Iv

Classic Joubert Syndrome

Joubert Syndrome Type A

Pure Joubert Syndrome

Cerebello-Oculo-Renal Syndrome 1

Joubert Syndrome-1

Joubert Syndrome, Type 1

Joubert'S Syndrome

Dermatomycosis

Dermatomycoses

Dyschromatosis Universalis Hereditaria

Duh

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus MICALL2 VGNC VGNC:31460
Mus musculus MICALL2 MGD MGI:2444818
Macaca mulatta MICALL2 VGNC VGNC:74620
Canis familiaris MICALL2 VGNC VGNC:54329
Rattus norvegicus MICALL2 RGD RGD:1307875
Felis catus MICALL2 VGNC VGNC:80593