2. Gene
  3. ST7 - suppression of tumorigenicity 7 Gene

ST7 - suppression of tumorigenicity 7 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：抑制致瘤性 7

种属: Homo sapiens

同用名: HELG; RAY1; SEN4; TSG7; ETS7q; FAM4A; FAM4A1

基因 ID: 7982 | 基因类型: protein coding

关于 ST7

Cytogenetic location: 7q31.2 Genomic coordinates (GRCh38): 7:116,953,501-117,230,176 (from NCBI)

This gene has 28 transcripts (splice variants), 208 orthologues and 1 paralogue. Ubiquitous expression in thyroid (RPKM 11.1), lung (RPKM 10.9) and 25 other tissues.

功能概要

该产品的基因映射到 7 号染色体上被确定为自闭症易感位点的区域。自闭症患者整个编码区的突变筛查未能识别表型特异性变异，表明该基因的编码突变不太可能与自闭症的病因有关。该基因产物的功能尚未确定。已经描述了编码该蛋白质不同亚型的转录变体。[RefSeq 提供，2008 年 7 月]

The gene for this product maps to a region on chromosome 7 identified as an autism-susceptibility locus. Mutation screening of the entire coding region in autistic individuals failed to identify phenotype-specific variants, suggesting that coding mutations for this gene are unlikely to be involved in the etiology of autism. The function of this gene product has not been determined. Transcript variants encoding different isoforms of this protein have been described. [provided by RefSeq, Jul 2008]

ST7 基因产物(11)

mRNA Protein Name
NM_001369598.1 NP_001356527.1 suppressor of tumorigenicity 7 protein isoform 3
NM_001369599.1 NP_001356528.1 suppressor of tumorigenicity 7 protein isoform 1
NM_001369600.1 NP_001356529.1 suppressor of tumorigenicity 7 protein isoform 2
NM_001369601.1 NP_001356530.1 suppressor of tumorigenicity 7 protein isoform 4
NM_001369602.1 NP_001356531.1 suppressor of tumorigenicity 7 protein isoform 6
NM_001369603.1 NP_001356532.1 suppressor of tumorigenicity 7 protein isoform 7
NM_001369604.1 NP_001356533.1 suppressor of tumorigenicity 7 protein isoform 9
NM_001369606.1 NP_001356535.1 suppressor of tumorigenicity 7 protein isoform 10
NM_001369607.1 NP_001356536.1 suppressor of tumorigenicity 7 protein isoform 11
NM_018412.4 NP_060882.2 suppressor of tumorigenicity 7 protein isoform 5
NM_021908.3 NP_068708.1 suppressor of tumorigenicity 7 protein isoform 8
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
30945288 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ST7 蛋白结构

ST7

ST7: ST7 protein (16 - 570)

  • 0
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  • 500
  • 585 a.a.
蛋白主名 其他名称

suppressor of tumorigenicity 7 protein

family with sequence similarity 4, subfamily A, member 1

关联疾病

疾病名称 别名
Autism

Autistic Disorder

Autism Susceptibility 1

Childhood Autism

Autistic Disorder Of Childhood Onset

Infantile Autism

Kanner'S Syndrome

Autistic
Gastric Dilatation

Stomach Dilatation
Facial Neuralgia
Neurilemmoma Of The Fifth Cranial Nerve

Trigeminal Schwannoma

Trigeminal Neurilemmoma
Trigeminal Nerve Neoplasm

Neoplasm Of Trigeminal Nerve

Tumor Of Trigeminal Nerve
Duodenal Obstruction
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-120541 ST-1006 Agonist 99.55% 否
HY-120541A ST-1006 Maleate Agonist / 否
HY-RS13854 ST7 Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS13855 ST7L Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus ST7 VGNC VGNC:49974
Felis catus ST7 VGNC VGNC:65734
Macaca mulatta ST7 VGNC VGNC:77899
Rattus norvegicus ST7 RGD RGD:1303148
Mus musculus ST7 MGD MGI:1927450
Canis familiaris ST7 VGNC VGNC:49656
Others ST7 NCBI
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