1. Gene
  2. BTNL8 - butyrophilin like 8 Gene

BTNL8 - butyrophilin like 8 Gene

中文名称:嗜乳脂蛋白样 8

种属: Homo sapiens

同用名: BTN9.2

基因 ID: 79908 | 基因类型: protein coding

关于 BTNL8

Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38): 5:180,899,159-180,950,906 (from NCBI)

This gene has 11 transcripts (splice variants), 24 orthologues and 15 paralogues. Biased expression in duodenum (RPKM 27.0), small intestine (RPKM 20.3) and 3 other tissues.

功能概要

预测启用信号受体结合活性。预计参与 T 细胞受体信号通路和细胞因子产生的调节。预测位于质膜中。预计在质膜外侧活跃。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

BTNL8 基因产物(6)

mRNA Protein Name
NM_001040462.3 NP_001035552.1 butyrophilin-like protein 8 isoform 2 precursor
NM_001159707.2 NP_001153179.1 butyrophilin-like protein 8 isoform 3 precursor
NM_001159708.2 NP_001153180.1 butyrophilin-like protein 8 isoform 4 precursor
NM_001159709.2 NP_001153181.1 butyrophilin-like protein 8 isoform 5
NM_001159710.2 NP_001153182.1 butyrophilin-like protein 8 isoform 6
NM_024850.3 NP_079126.1 butyrophilin-like protein 8 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
21982860 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

BTNL8 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (19 - 121)

PRY

PRY: SPRY-associated domain (290 - 336)

SPRY

SPRY: SPRY domain (339 - 444)

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  • 500 a.a.
蛋白主名 其他名称

butyrophilin-like protein 8

B7-H5 costimulatory molecule

重组 BTNL8 蛋白

目录号 产品名 蛋白编号 纯度
HY-P79382 BTNL8 Protein, Human (HEK293, hFc) Q6UX41-1 (Q18-K238) ≥95%

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta BTNL8 VGNC VGNC:110483
Rattus norvegicus BTNL8 RGD RGD:1587504
Others BTNL8 NCBI