2. Gene
  3. DOK3 - docking protein 3 Gene

DOK3 - docking protein 3 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：对接蛋白 3

种属: Homo sapiens

同用名: DOKL

基因 ID: 79930 | 基因类型: protein coding

关于 DOK3

Cytogenetic location: 5q35.3 Genomic coordinates (GRCh38): 5:177,501,904-177,511,100 (from NCBI)

This gene has 13 transcripts (splice variants), 122 orthologues and 7 paralogues. Biased expression in bone marrow (RPKM 31.4), spleen (RPKM 15.5) and 11 other tissues.

功能概要

预测参与 Ras 蛋白信号转导和跨膜受体蛋白酪氨酸激酶信号通路。预测位于富含 ficolin-1 的颗粒膜和质膜。预计在细胞质中有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to be involved in Ras protein signal transduction and transmembrane receptor protein tyrosine kinase signaling pathway. Predicted to be located in ficolin-1-rich granule membrane and plasma membrane. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

DOK3 基因产物(14)

mRNA Protein Name
NM_001144875.2 NP_001138347.1 docking protein 3 isoform 2
NM_001144876.2 NP_001138348.1 docking protein 3 isoform 3
NM_001308235.3 NP_001295164.1 docking protein 3 isoform 1
NM_001308236.3 NP_001295165.1 docking protein 3 isoform 1
NM_001375794.1 NP_001362723.1 docking protein 3 isoform 1
NM_001375795.1 NP_001362724.1 docking protein 3 isoform 1
NM_001375796.1 NP_001362725.1 docking protein 3 isoform 1
NM_001375797.2 NP_001362726.1 docking protein 3 isoform 1
NM_001375798.1 NP_001362727.1 docking protein 3 isoform 2
NM_001375799.2 NP_001362728.1 docking protein 3 isoform 2
NM_001384137.1 NP_001371066.1 docking protein 3 isoform 1
NM_001384138.1 NP_001371067.1 docking protein 3 isoform 4
NM_001384139.1 NP_001371068.1 docking protein 3 isoform 4
NM_024872.4 NP_079148.3 docking protein 3 isoform 1

DOK3 蛋白结构

IRS

IRS: PTB domain (IRS-1 type) (216 - 311)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 496 a.a.
蛋白主名 其他名称

docking protein 3

Dok-like protein

DOK3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
DOK3 Q7L591 EGFR Homo sapiens P00533
Ub Reconstruction
27956147
种属内
DOK3 Q7L591 EGFR Homo sapiens P00533
Anti Tag CoIP
27956147
种属内
DOK3 Q7L591 TRAF1 Homo sapiens Q13077
Y2H Array
25416956
种属内
DOK3 Q7L591 TRAF1 Homo sapiens Q13077
Validated Y2H
25416956
种属内
DOK3 Q7L591 RBPMS Homo sapiens Q93062
Y2H Array
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Histiocytic And Dendritic Cell Cancer

Histiocytic And Dendritic Cell
Histiocytic Sarcoma

Malignant Histiocytosis
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS03935 DOK3 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus DOK3 RGD RGD:1311840
Canis familiaris DOK3 VGNC VGNC:40057
Mus musculus DOK3 MGD MGI:1351490
Macaca mulatta DOK3 VGNC VGNC:71897
Felis catus DOK3 VGNC VGNC:61582
Bos taurus DOK3 VGNC VGNC:28167
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