2. Gene
  3. TTC26 - tetratricopeptide repeat domain 26 Gene

TTC26 - tetratricopeptide repeat domain 26 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：四肽重复结构域 26

种属: Homo sapiens

同用名: BRENS; DYF13; IFT56; dyf-13

基因 ID: 79989 | 基因类型: protein coding

关于 TTC26

Cytogenetic location: 7q34 Genomic coordinates (GRCh38): 7:139,133,778-139,191,986 (from NCBI)

This gene has 10 transcripts (splice variants), 226 orthologues and is associated with 1 phenotype. Broad expression in testis (RPKM 5.7), thyroid (RPKM 2.6) and 23 other tissues.

功能概要

预测启用纤毛内转运粒子 B 结合活性。预计参与纤毛组织；蛋白质定位于纤毛；和平滑的信号通路。预计在 manchette 组件的上游或内部起作用。预测位于纤毛中。预计是纤毛内转运粒子 B 的一部分。预计在睫状基体和睫状基底部有活性。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in cilium organization; protein localization to cilium; and smoothened signaling pathway. Predicted to act upstream of or within manchette assembly. Predicted to be located in cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in ciliary basal body and ciliary base. [provided by Alliance of Genome Resources, Apr 2022]

TTC26 基因产物(9)

mRNA Protein Name
NM_001144920.3 NP_001138392.1 intraflagellar transport protein 56 isoform 2
NM_001144923.3 NP_001138395.1 intraflagellar transport protein 56 isoform 3
NM_001287512.2 NP_001274441.1 intraflagellar transport protein 56 isoform 4
NM_001287513.2 NP_001274442.1 intraflagellar transport protein 56 isoform 5
NM_001318333.2 NP_001305262.1 intraflagellar transport protein 56 isoform 6
NM_001321740.2 NP_001308669.1 intraflagellar transport protein 56 isoform 7
NM_001321741.2 NP_001308670.1 intraflagellar transport protein 56 isoform 8
NM_001321742.2 NP_001308671.1 intraflagellar transport protein 56 isoform 9
NM_024926.4 NP_079202.2 intraflagellar transport protein 56 isoform 1
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cilium assembly IMP
IMP: 通过突变表型推断
31595528 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cilium IMP
IMP: 通过突变表型推断
31595528 GOA
part of intraciliary transport particle B IPI
IPI: 通过物理相互作用推断
26980730 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

TTC26 蛋白结构

TPR_11

TPR_11: TPR repeat (64 - 112)

TPR_9

TPR_9: Tetratricopeptide repeat (158 - 225)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 554 a.a.
蛋白主名 其他名称

intraflagellar transport protein 56

TPR repeat protein 26

关联疾病

疾病名称 别名
Biliary, Renal, Neurologic, And Skeletal Syndrome

BRENS

Brens Syndrome
Hydrocephalus

Hydrocephalus, Nonsyndromic, Autosomal Recessive

Hydrocephalus, X-Linked

Hydrocephalus Adverse Event

Hydrocephaly Nos
Caroli Disease

Caroli Disease Isolated

Congenital Polycystic Dilatation Of Intrahepatic Bile Ducts

Cystic Dilatation Of The Intrahepatic Biliary Tree

Caroli Syndrome

Carolis Disease
Bardet-Biedl Syndrome 15

BBS15

Bardet-Biedl Syndrome, Type 15
Bardet-Biedl Syndrome 3

BBS3

Bardet-Biedl Syndrome, Type 3
Meckel Syndrome, Type 2

MKS2

Meckel Syndrome 2

Meckel-Gruber Syndrome, Type 2

Meckel Syndrome Type 2
Meckel Syndrome, Type 5

Meckel Syndrome 5

MKS5

Meckel-Gruber Syndrome, Type 5
Situs Inversus

Situs Inversus Viscerum

Laterality Sequence

Complete Transposition

Siv
Bardet-Biedl Syndrome

Bbs

Biedl-Bardet Syndrome
Short-Rib Thoracic Dysplasia 3 With Or Without Polydactyly

Asphyxiating Thoracic Dystrophy 3

Saldino-Noonan Syndrome

SRTD3

Atd3

Srps1

Srps3

Verma-Naumoff Syndrome

Srps2b

Short Rib-Polydactyly Syndrome, Verma-Naumoff Type

Short Rib-Polydactyly Syndrome, Type I

Polydactyly With Neonatal Chondrodystrophy, Type I

Polydactyly With Neonatal Chondrodystrophy, Type Iii

Short Rib-Polydactyly Syndrome, Type Iib

Short Rib-Polydactyly Syndrome Type 3

Polydactyly With Neonatal Chondrodystrophy Type Iii

Short Rib-Polydactyly Syndrome Type Iii

Short Rib-Polydactyly Syndrome Type 1

Short Rib-Polydactyly Syndrome, Saldino-Noonan Type

Majewski Syndrome

Short Rib-Polydactyly Syndrome, Type Iii

Type I Short Rib Polydactyly Syndrome

Srps Type 3

Short Rib Polydactyly Syndrome Verma Naumoff Type

Verma Naumoff Syndrome

Polydactyly With Neonatal Chondrodystrophy Type 1

Srps Type 1

Short Rib-Polydactyly Syndrome Saldino-Noonan Type

Jatd

Jeune Asphyxiating Thoracic Dystrophy

Jeune Syndrome 3

Polydactyly With Neonatal Chondrodystrophy Type I

Short Rib-Polydactyly Syndrome Type I

Short Rib-Polydactyly Syndrome Type Iib

Srps Type Iib

Srps Type Iii
Short-Rib Thoracic Dysplasia 12

Beemer-Langer Syndrome

Type Iv Short Rib Polydactyly Syndrome

Short Rib-Polydactyly Syndrome Type 4

Short Rib-Polydactyly Syndrome, Beemer Type

SRTD12

Short Rib-Polydactyly Syndrome, Type Iv

Srps4

Srps Iv

Short Rib Syndrome, Beemer Type

Beemer Langer Syndrome

Srps Type 4

Short Rib Polydactyly Syndrome Beemer-Langer Type

Short Rib-Polydactyly Syndrome Beemer Type

Short Rib-Polydactyly Syndrome Type Iv

Short Rib-Polydactyly Syndrome, Beemer-Langer Type
Polycystic Liver Disease

Autosomal Dominant Polycystic Liver Disease

Isolated Polycystic Liver Disease

Pcld

Congenital Cystic Liver Disease

Congenital Hepatic Cyst

Fibrocystic Liver Disease

Isolated Autosomal Dominant Polycystic Liver Disease

Adpcld

Liver Disease, Polycystic

Multiple Cysts Of Liver

Pld - [Polycystic Liver Disease]

Polycystic Liver Disorder

Polycystic Liver

Congenital Polycystic Disease Of Liver

Congenital Polycystic Liver Disease
Joubert Syndrome 1

Joubert Syndrome

Jbts

Cerebellooculorenal Syndrome 1

JBTS1

Joubert-Boltshauser Syndrome

Cerebelloparenchymal Disorder Iv

Cpd4

Cors1

Joubert Syndrome And Related Disorders

Jsrd

Familial Aplasia Of The Vermis

Joubert Syndrome Related Disorders

Js

Cerebellar Vermis Agenesis

Cerebelloparenchymal Disorder 4

Agenesis Of Cerebellar Vermis

Cerebello-Oculo-Renal Syndrome

Cors

Joubert-Bolthauser Syndrome

Cpd Iv

Classic Joubert Syndrome

Joubert Syndrome Type A

Pure Joubert Syndrome

Cerebello-Oculo-Renal Syndrome 1

Joubert Syndrome-1

Joubert Syndrome, Type 1

Joubert'S Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15204 TTC26 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Canis familiaris TTC26 VGNC VGNC:47947
Macaca mulatta TTC26 VGNC VGNC:79341
Mus musculus TTC26 MGD MGI:2444853
Rattus norvegicus TTC26 RGD RGD:1561363
Bos taurus TTC26 VGNC VGNC:36465
Felis catus TTC26 VGNC VGNC:66662
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