2. Gene
  3. MYO19 - myosin XIX Gene

MYO19 - myosin XIX Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：肌球蛋白 XIX

种属: Homo sapiens

同用名: MYOHD1

基因 ID: 80179 | 基因类型: protein coding

关于 MYO19

Cytogenetic location: 17q12 Genomic coordinates (GRCh38): 17:36,495,636-36,544,815 (from NCBI)

This gene has 27 transcripts (splice variants), 1 gene allele, 195 orthologues and 43 paralogues. Ubiquitous expression in skin (RPKM 10.8), esophagus (RPKM 7.0) and 25 other tissues.

功能概要

启用肌动蛋白结合活动。参与调节胞质分裂和调节线粒体裂变。沿着肌动蛋白丝在线粒体迁移的上游或内部起作用。位于胞质溶胶和线粒体外膜。 [由基因组资源联盟提供，2022 年 4 月]

Enables actin binding activity. Involved in regulation of cytokinesis and regulation of mitochondrial fission. Acts upstream of or within mitochondrion migration along actin filament. Located in cytosol and mitochondrial outer membrane. [provided by Alliance of Genome Resources, Apr 2022]

MYO19 基因产物(3)

mRNA Protein Name
NM_001033580.3 NP_001028752.1 unconventional myosin-XIX isoform 3
NM_001163735.2 NP_001157207.1 unconventional myosin-XIX isoform 2
NM_025109.6 NP_079385.2 unconventional myosin-XIX isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables ATP hydrolysis activity IDA
IDA: 通过直接分析推断
23568824 GOA
enables actin binding IDA
IDA: 通过直接分析推断
23568824 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
acts upstream of or within mitochondrion migration along actin filament IDA
IDA: 通过直接分析推断
19932026 GOA
involved in regulation of cytokinesis IMP
IMP: 通过突变表型推断
25447992 GOA
involved in regulation of mitochondrial fission IMP
IMP: 通过突变表型推断
25447992 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrial outer membrane IDA
IDA: 通过直接分析推断
27126804 GOA
located in mitochondrion IDA
IDA: 通过直接分析推断
23568824 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MYO19 蛋白结构

Myosin_head

Myosin_head: Myosin head (motor domain) (38 - 674)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 970 a.a.
蛋白主名 其他名称

unconventional myosin-XIX

myosin head domain containing 1

MYO19 抗体

目录号 产品名 应用 反应物种
HY-P83537 MYO19 Antibody (YA3282) WB Human, Mouse

关联疾病

疾病名称 别名
Glycosylphosphatidylinositol Biosynthesis Defect 11

GPIBD11

Hyperphosphatasia With Mental Retardation Syndrome 5

Hpmrs5

Hyperphosphatasia With Mental Retardation Syndrome, Type 5
Cleft Palate, Isolated

Cleft Palate

Isolated Cleft Palate

CPI

Cp

Palatoschisis

Cleft Palate Isolated

Uranostaphyloschisis

Congenital Fissure Of Palate

Cleft Of Secondary Palate
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08936 MYO19 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus MYO19 RGD RGD:1559961
Macaca mulatta MYO19 VGNC VGNC:75026
Mus musculus MYO19 MGD MGI:1913446
Canis familiaris MYO19 VGNC VGNC:43559
Felis catus MYO19 VGNC VGNC:63686
Bos taurus MYO19 VGNC VGNC:31815
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