2. Gene
  3. AKNA - AT-hook transcription factor Gene

AKNA - AT-hook transcription factor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：AT 钩转录因子

种属: Homo sapiens

基因 ID: 80709 | 基因类型: protein coding

关于 AKNA

Cytogenetic location: 9q32 Genomic coordinates (GRCh38): 9:114,330,504-114,398,472 (from NCBI)

This gene has 9 transcripts (splice variants), 156 orthologues and 1 paralogue. Broad expression in spleen (RPKM 28.7), lymph node (RPKM 23.1) and 20 other tissues.

功能概要

预测启用 DNA 结合活性。参与 RNA 聚合酶 II 对转录的正调控。位于中心体；胞质溶胶；和核腔。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable DNA binding activity. Involved in positive regulation of transcription by RNA polymerase II. Located in centrosome; cytosol; and nuclear lumen. [provided by Alliance of Genome Resources, Apr 2022]

AKNA 基因产物(3)

mRNA Protein Name
NM_001317950.2 NP_001304879.1 microtubule organization protein AKNA isoform 1
NM_001317952.1 NP_001304881.1 microtubule organization protein AKNA isoform 2
NM_030767.5 NP_110394.3 microtubule organization protein AKNA isoform 1
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16000308 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: 通过直接分析推断
11268217 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

AKNA 蛋白结构

AKNA

AKNA: AT-hook-containing transcription factor (592 - 697)

  • 0
  • 300
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  • 1200
  • 1439 a.a.
蛋白主名 其他名称

microtubule organization protein AKNA

AKNA transcript F2

AKNA 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
AKNA Q7Z591 CD2BP2 Homo sapiens O95400
NMR
16000308
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Vogt-Koyanagi-Harada Disease

Uveomeningoencephalitic Syndrome

Uveomenigitic Syndrome

Vogt-Koyanagi-Harada Syndrome

Harada'S Disease

Vogt-Koyanagi Syndrome

Vkh Disease

Vkh Syndrome

Vkh
Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00529 AKNA Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus AKNA RGD RGD:1308202
Mus musculus AKNA MGD MGI:2140340
Bos taurus AKNA VGNC VGNC:55031
Macaca mulatta AKNA VGNC VGNC:69684
Canis familiaris AKNA VGNC VGNC:37767
Felis catus AKNA VGNC VGNC:59722
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