2. Gene
  3. VOPP1 - VOPP1 WW domain binding protein Gene

VOPP1 - VOPP1 WW domain binding protein Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：VOPP1 WW 结构域结合蛋白

种属: Homo sapiens

同用名: ECOP; GASP; WBP1L2

基因 ID: 81552 | 基因类型: protein coding

关于 VOPP1

Cytogenetic location: 7p11.2 Genomic coordinates (GRCh38): 7:55,434,964-55,572,502 (from NCBI)

This gene has 17 transcripts (splice variants) and 206 orthologues. Ubiquitous expression in lymph node (RPKM 19.1), appendix (RPKM 14.7) and 25 other tissues.

功能概要

位于细胞质囊泡膜和核内体中。是细胞器膜的组成部分。 [由基因组资源联盟提供，2022 年 4 月]

Located in cytoplasmic vesicle membrane and endosome. Is integral component of organelle membrane. [provided by Alliance of Genome Resources, Apr 2022]

VOPP1 基因产物(13)

mRNA Protein Name
NM_001284282.2 NP_001271211.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 2
NM_001284283.2 NP_001271212.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 3
NM_001284284.1 NP_001271213.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 4
NM_001321242.1 NP_001308171.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 5
NM_001321243.2 NP_001308172.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 6 precursor
NM_001321244.2 NP_001308173.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 7
NM_001321246.2 NP_001308175.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 8 precursor
NM_001321247.2 NP_001308176.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 9 precursor
NM_001321248.2 NP_001308177.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 10 precursor
NM_001321249.2 NP_001308178.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 11 precursor
NM_001321250.2 NP_001308179.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 11 precursor
NM_001321251.1 NP_001308180.1 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 11 precursor
NM_030796.5 NP_110423.3 vesicular, overexpressed in cancer, prosurvival protein 1 isoform 1 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables enzyme binding IPI
IPI: 通过物理相互作用推断
30285739 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
30285739 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasmic vesicle membrane IDA
IDA: 通过直接分析推断
20571887 GOA
located in late endosome IDA
IDA: 通过直接分析推断
30285739 GOA
located in lysosome IDA
IDA: 通过直接分析推断
30285739 GOA
located in organelle membrane IDA
IDA: 通过直接分析推断
20571887 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

vesicular, overexpressed in cancer, prosurvival protein 1

EGFR-coamplified and overexpressed protein

VOPP1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
VOPP1 Q96AW1 WWOX Homo sapiens Q9NZC7
Anti Tag CoIP
33961781
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Glioblastoma

Glioblastoma Multiforme

Gbm

Adult Glioblastoma Multiforme

Grade Iv Adult Astrocytic Tumor

Primary Glioblastoma Multiforme

Spongioblastoma Multiforme

Adult Glioblastoma

Primary Glioblastoma
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15668 VOPP1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus VOPP1 VGNC VGNC:80754
Mus musculus VOPP1 MGD MGI:2141658
Macaca mulatta VOPP1 VGNC VGNC:79950
Canis familiaris VOPP1 VGNC VGNC:54387
Rattus norvegicus VOPP1 RGD RGD:1306494
Bos taurus VOPP1 VGNC VGNC:49588
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