1. Gene
  2. Sctr - secretin receptor Gene

Sctr - secretin receptor Gene

中文名称:分泌素受体

种属: Rattus norvegicus

基因 ID: 81779 | 基因类型: protein coding

关于 Sctr

Primary_assembly 13: 31,127,858-31,180,189 forward strand.mRatBN7.2:CM026986.1

This gene has 3 transcripts (splice variants), 130 orthologues, 42 paralogues and is associated with 1 phenotype. Biased expression in Heart (RPKM 66.8), Spleen (RPKM 27.6) and 6 other tissues.

功能概要

该基因编码的蛋白可启动肽结合活性和分泌素受体活性。参与大脑发育和 cAMP 介导的信号传导的正向调节。预测位于细胞质微管中。预计在质膜上有活性。与人类 SCTR(分泌素受体)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables peptide binding activity and Secretin Receptor activity. Involved in brain development and positive regulation of cAMP-mediated signaling. Predicted to be located in cytoplasmic microtubule. Predicted to be active in plasma membrane. Orthologous to human SCTR (Secretin Receptor). [provided by Alliance of Genome Resources, Apr 2022]

Sctr 基因产物(1)

mRNA Protein Name
NM_031115.1 NP_112377.1 secretin receptor precursor
基因本体论
  • 分子功能
  • 生物过程
分子功能 GO 注释 逻辑证据 参考文献 来源
enables peptide binding IDA
IDA: 通过直接分析推断
1646711 RGD
enables peptide binding IPI
IPI: 通过物理相互作用推断
12403838 RGD
enables secretin receptor activity IDA
IDA: 通过直接分析推断
1646711 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in regulation of cAMP/PKA signal transduction IMP
IMP: 通过突变表型推断
12403838 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Sctr 蛋白结构

HormR

HormR: smart00008 (79 - 146)

7tmB1_secretin

7tmB1_secretin: cd15275 (153 - 419)

7tmB1_secretin

7tmB1_secretin: cd15275 (155 - 180)

7tmB1_secretin

7tmB1_secretin: cd15275 (189 - 211)

7tmB1_secretin

7tmB1_secretin: cd15275 (230 - 257)

7tmB1_secretin

7tmB1_secretin: cd15275 (269 - 289)

7tmB1_secretin

7tmB1_secretin: cd15275 (305 - 334)

7tmB1_secretin

7tmB1_secretin: cd15275 (350 - 377)

7tmB1_secretin

7tmB1_secretin: cd15275 (381 - 406)

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  • 400
  • 464 a.a.
蛋白主名 其他名称

secretin receptor

SCT-R

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sctr NCBI NCBI:6344