1. Gene
  2. UBL4A - ubiquitin like 4A Gene

UBL4A - ubiquitin like 4A Gene

中文名称:泛素样 4A

种属: Homo sapiens

同用名: GDX; G6PD; GET5; MDY2; UBL4; TMA24; DX254E; DXS254E

基因 ID: 8266 | 基因类型: protein coding

关于 UBL4A

Cytogenetic location: Xq28 Genomic coordinates (GRCh38): X:154,483,717-154,486,615 (from NCBI)

This gene has 7 transcripts (splice variants), 178 orthologues and 10 paralogues. Ubiquitous expression in heart (RPKM 16.9), brain (RPKM 12.9) and 25 other tissues.

功能概要

启用伴侣结合活动。参与尾锚定膜蛋白插入 ER 膜。位于胞质溶胶中;膜;和核质。 BAT3 复合体的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables chaperone binding activity. Involved in tail-anchored membrane protein insertion into ER membrane. Located in cytosol; membrane; and nucleoplasm. Part of BAT3 complex. [provided by Alliance of Genome Resources, Apr 2022]

UBL4A 基因产物(1)

mRNA Protein Name
NM_014235.5 NP_055050.1 ubiquitin-like protein 4A
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
19615732 GOA
enables protein-folding chaperone binding IPI
IPI: 通过物理相互作用推断
25535373 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of BAT3 complex IDA
IDA: 通过直接分析推断
20676083 GOA
part of BAT3 complex IPI
IPI: 通过物理相互作用推断
25535373 GOA
located in cytoplasm IDA
IDA: 通过直接分析推断
21636303 GOA
located in cytosol IDA
IDA: 通过直接分析推断
20676083 GOA
located in membrane IDA
IDA: 通过直接分析推断
23246001 GOA
located in nucleus IDA
IDA: 通过直接分析推断
21636303 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

UBL4A 蛋白结构

ubiquitin

ubiquitin: Ubiquitin family (6 - 73)

  • 0
  • 100
  • 157 a.a.
蛋白主名 其他名称

ubiquitin-like protein 4A

ubiquitin-like 4

UBL4A 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra UBL4A P11441 PER2 Homo sapiens O15055
Y2H Prey Pooling
32296183
Intra UBL4A P11441 PER2 Homo sapiens O15055
Y2H Array
32296183
Intra UBL4A P11441 TRIM54 Homo sapiens Q9BYV2
Y2H Array
32296183
Intra UBL4A P11441 TRIM54 Homo sapiens Q9BYV2
Y2H Prey Pooling
32296183
Intra UBL4A P11441 TRIM54 Homo sapiens Q9BYV2
Validated Y2H
32296183
Intra UBL4A P11441 CHAT Homo sapiens P28329-3
Validated Y2H
32814053
Intra UBL4A P11441 CHAT Homo sapiens P28329-3
Y2H Array
32814053
Intra UBL4A P11441 CHAT Homo sapiens P28329-3
Y2H Pooling
32814053
Intra UBL4A P11441 SGTA Homo sapiens O43765
Y2H Array
32296183
Intra UBL4A P11441 SGTA Homo sapiens O43765
Y2H Prey Pooling
32296183
Intra UBL4A P11441 SGTA Homo sapiens O43765
Anti Tag CoIP
19615732
Intra UBL4A P11441 FGFR3 Homo sapiens P22607
Validated Y2H
32814053
Intra UBL4A P11441 FGFR3 Homo sapiens P22607
Y2H Array
32814053
Intra UBL4A P11441 FGFR3 Homo sapiens P22607
Y2H Pooling
32814053
Intra UBL4A P11441 TRAF4 Homo sapiens Q9BUZ4
Validated Y2H
32296183
Intra UBL4A P11441 CDCA7L Homo sapiens Q96GN5
Y2H Prey Pooling
25416956
Intra UBL4A P11441 CDCA7L Homo sapiens Q96GN5
Y2H Array
25416956
Intra UBL4A P11441 CDCA7L Homo sapiens Q96GN5
Validated Y2H
25416956
Intra UBL4A P11441 S100P Homo sapiens P25815
Y2H Array
32296183
Intra UBL4A P11441 S100P Homo sapiens P25815
Validated Y2H
32296183
Intra UBL4A P11441 S100P Homo sapiens P25815
Y2H Prey Pooling
32296183
Intra UBL4A P11441 SGTB Homo sapiens Q96EQ0
Validated Y2H
32296183
Intra UBL4A P11441 MEOX2 Homo sapiens P50222
Validated Y2H
25416956
Intra UBL4A P11441 MEOX2 Homo sapiens P50222
Y2H Prey Pooling
25416956
Intra UBL4A P11441 ERP27 Homo sapiens Q96DN0
Validated Y2H
32296183
Intra UBL4A P11441 ERP27 Homo sapiens Q96DN0
Y2H Array
32296183
Intra UBL4A P11441 ERP27 Homo sapiens Q96DN0
Y2H Prey Pooling
32296183
Cross UBL4A P11441 vif Human immunodeficiency virus P12504
Pull Down
22190034
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta UBL4A VGNC VGNC:78702
Felis catus UBL4A VGNC VGNC:66774
Mus musculus UBL4A MGD MGI:95049
Rattus norvegicus UBL4A RGD RGD:1563983
Canis familiaris UBL4A VGNC VGNC:48077