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  2. Aplnr - apelin receptor Gene

Aplnr - apelin receptor Gene

中文名称:apelin受体

种属: Rattus norvegicus

同用名: Apj; Agtrl1

基因 ID: 83518 | 基因类型: protein coding

关于 Aplnr

Primary_assembly 3: 70,217,385-70,221,050 forward strand.mRatBN7.2:CM026976.1

This gene has 1 transcript (splice variant), 172 orthologues, 8 paralogues and is associated with 2 phenotypes.

功能概要

预测该基因编码的蛋白可启动apelin受体活性。参与G蛋白偶联受体信号通路;负调节 cAMP 介导的信号;和调节体液水平。位于质膜。与人类 APLNR(apelin 受体)同源。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable apelin receptor activity. Involved in G protein-coupled receptor signaling pathway; negative regulation of cAMP-mediated signaling; and regulation of body fluid levels. Located in plasma membrane. Orthologous to human APLNR (apelin receptor). [provided by Alliance of Genome Resources, Apr 2022]

Aplnr 基因产物(1)

mRNA Protein Name
NM_031349.2 NP_112639.1 apelin receptor
基因本体论
  • 生物过程
  • 细胞组分
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in G protein-coupled receptor signaling pathway IMP
IMP: 通过突变表型推断
11359874 RGD
involved in negative regulation of cAMP-mediated signaling IMP
IMP: 通过突变表型推断
11359874 RGD
involved in regulation of body fluid levels IMP
IMP: 通过突变表型推断
12787050 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
11359874 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

Aplnr 蛋白结构

7tmA_Apelin_R

7tmA_Apelin_R: cd15190 (16 - 317)

7tmA_Apelin_R

7tmA_Apelin_R: cd15190 (27 - 53)

7tmA_Apelin_R

7tmA_Apelin_R: cd15190 (61 - 86)

7tmA_Apelin_R

7tmA_Apelin_R: cd15190 (99 - 129)

7tmA_Apelin_R

7tmA_Apelin_R: cd15190 (142 - 163)

7tmA_Apelin_R

7tmA_Apelin_R: cd15190 (195 - 224)

7tmA_Apelin_R

7tmA_Apelin_R: cd15190 (238 - 268)

7tmA_Apelin_R

7tmA_Apelin_R: cd15190 (285 - 310)

  • 0
  • 100
  • 200
  • 300
  • 377 a.a.
蛋白主名 其他名称

apelin receptor

B78

G-protein coupled receptor APJ

GPCR34

angiotensin receptor-like 1

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Aplnr NCBI NCBI:187