UCK1 - uridine-cytidine kinase 1 Gene

中文名称：尿苷胞苷激酶 1

种属: Homo sapiens

同用名: URK1

关于 UCK1

功能概要

该基因编码尿苷-胞苷激酶，该激酶催化尿苷和胞苷磷酸化为尿苷一磷酸 (UMP) 和胞苷一磷酸 (CMP) ，但不催化脱氧核糖核苷或嘌呤核糖核苷的磷酸化。该酶还可以磷酸化尿苷和胞苷类似物，并使用 ATP 和 GTP 作为磷酸盐供体。可变剪接导致编码不同异构体的多个剪接变体。[RefSeq 提供，2012 年 5 月]

This gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This Enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012]