2. Gene
  3. RXRG - retinoid X receptor gamma Gene

RXRG - retinoid X receptor gamma Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：视黄醇 X 受体 γ

种属: Rattus norvegicus

基因 ID: 83574 | 基因类型: protein coding

关于 RXRG

Primary_assembly 13: 79,743,563-79,785,167 forward strand.mRatBN7.2:CM026986.1

This gene has 2 transcripts (splice variants), 277 orthologues, 11 paralogues and is associated with 5 phenotypes. Biased expression in Heart (RPKM 248.), Muscle (RPKM 23.6) and 5 other tissues.

功能概要

预测该基因编码的蛋白具有相同的蛋白质结合活性；核受体活性；和视黄酸反应元件结合活性。参与多个过程，包括神经系统发育；髓鞘形成的调节；和对视黄酸的反应。位于核内。该基因的人类直系同源物与肺非小细胞癌有关。与人类 RXRG（类视黄醇 X 受体γ）同源。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable identical protein binding activity; nuclear receptor activity; and retinoic acid-responsive element binding activity. Involved in several processes, including nervous system development; regulation of myelination; and response to retinoic acid. Located in nucleus. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human RXRG (retinoid X receptor gamma). [provided by Alliance of Genome Resources, Apr 2022]

RXRG 基因产物(1)

mRNA Protein Name
NM_031765.1 NP_113953.1 retinoic acid receptor RXR-gamma
基因本体论
  • 生物过程
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in cellular response to hormone stimulus IEP
IEP: 通过表达模式推断
10328854 RGD
involved in heart development IEP
IEP: 通过表达模式推断
10328854 RGD
involved in neuron differentiation IEP
IEP: 通过表达模式推断
15664689 RGD
involved in peripheral nervous system development IEP
IEP: 通过表达模式推断
9682978 RGD
involved in regulation of myelination IDA
IDA: 通过直接分析推断
20648638 RGD
involved in response to organic cyclic compound IEP
IEP: 通过表达模式推断
18923996 RGD
involved in response to retinoic acid IEP
IEP: 通过表达模式推断
17161848 RGD
involved in skeletal muscle tissue development IEP
IEP: 通过表达模式推断
9389449 RGD
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RXRG 蛋白结构

Nuc_recep-AF1

Nuc_recep-AF1: pfam11825 (24 - 133)

NR_DBD_RXR

NR_DBD_RXR: cd06956 (136 - 212)

NR_LBD_RXR_like

NR_LBD_RXR_like: cd06943 (232 - 441)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 464 a.a.
蛋白主名 其他名称

retinoic acid receptor RXR-gamma

RXR gamma-1

nuclear receptor subfamily 2 group B member 3

retinoic X receptor gamma-1

retinoic acid receptor RXR-gamma-like

相关产品

Pre-clinical Phase
生物活性分子 (4)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12363 RXRG Human Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12364 Rxrg Mouse Pre-designed siRNA Set A Pre-designed Sets / 否
HY-RS12365 RXRG Rat Pre-designed siRNA Set A Pre-designed Sets / 否
HY-160212 JP3000 Agonist / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens RXRG NCBI NCBI:6258
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