2. Gene
  3. REG4 - regenerating family member 4 Gene

REG4 - regenerating family member 4 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：重生家族成员 4

种属: Homo sapiens

同用名: GISP; RELP; REG-IV

基因 ID: 83998 | 基因类型: protein coding

关于 REG4

Cytogenetic location: 1p12 Genomic coordinates (GRCh38): 1:119,794,017-119,811,460 (from NCBI)

This gene has 4 transcripts (splice variants), 111 orthologues and 5 paralogues. Biased expression in small intestine (RPKM 174.4), colon (RPKM 137.8) and 2 other tissues.

功能概要

启用肝素结合活性和甘露聚糖结合活性。预计在对细菌的反应上游或反应内起作用。位于细胞质中。 [由基因组资源联盟提供，2022 年 4 月]

Enables heparin binding activity and mannan binding activity. Predicted to act upstream of or within response to bacterium. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]

REG4 基因产物(3)

mRNA Protein Name
NM_001159352.2 NP_001152824.1 regenerating islet-derived protein 4 isoform 1 precursor
NM_001159353.2 NP_001152825.1 regenerating islet-derived protein 4 isoform 2 precursor
NM_032044.4 NP_114433.1 regenerating islet-derived protein 4 isoform 1 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
NOT enables calcium ion binding IDA
IDA: 通过直接分析推断
20692269 GOA
enables heparin binding IDA
IDA: 通过直接分析推断
20692269 GOA
enables mannan binding IDA
IDA: 通过直接分析推断
20692269 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cytoplasm IDA
IDA: 通过直接分析推断
12819006 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

REG4 蛋白结构

Lectin_C

Lectin_C: Lectin C-type domain (49 - 155)

  • 0
  • 100
  • 158 a.a.
蛋白主名 其他名称

regenerating islet-derived protein 4

REG-4

重组 REG4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71257 REG-4 Protein, Human (HEK293, His) Q9BYZ8-1 (D23-P158) ≥95%
HY-P74597 REG-4 Protein, Human (HEK293, Fc) Q9BYZ8-1 (D23-P158) ≥95%

关联疾病

疾病名称 别名
Ulcerative Colitis

Colitis Gravis

Left Sided Ulcerative Colitis

Left-Sided Ulcerative Colitis

Idiopathic Proctocolitis

Inflammatory Bowel Disease, Ulcerative Colitis Type

Uc

Colitis Ulcerative

Colitis, Ulcerative

Chronic Left-Sided Ulcerative Colitis

Uc - [Ulcerative Colitis]

Chronic Ulcerative Enteritis

Mucosal Proctocolitis

Ulcerative Mucosal Proctocolitis

Left Hemicolitis
Pseudomyxoma Peritonei

Adenomucinosis

Gelatinous Ascites

Pmp

Mucinous Ascites

Syndrome Of Pseudomyxoma Peritonei
Bladder Urachal Carcinoma

Urachal Cancer

Urachal Carcinoma
Urachus Cancer

Malignant Tumor Of Urachus
Cystadenoma

Cystoma

Craniopharyngioma
Colitis
Crohn'S Disease

Crohn Disease

Pediatric Crohn'S Disease

Regional Enteritis

Crohn'S Disease Of Large Bowel

Granulomatous Colitis

Enteritis, Granulomatous

Enteritis

Crohn'S Disease Of Colon

Colitis, Granulomatous

Crohn'S Enteritis

Enteritis, Regional

Ileitis

Adenoviral Enteritis

Acute Gastroenteropathy Due To Norwalk Agent

Viral Gastroenteritis Due To Norwalk Agent

Winter Vomiting

Epidemic Winter Vomiting Disease

Small Round Structured Virus Enteritis

Epidemic Vomiting Syndrome

Epidemic Vomiting

Epidemic Nausea

Epidemic Viral Gastroenteritis Due To Norwalk Virus

Noroviral Enteritis

Crohn Disease Nos

Crohns

Cd - [Crohn'S Disease]

Regional Enteritis Of Bowel

Crohn'S Regional Enteritis

Cobble-Stone Appearance Of Intestine

Intestinal Ulcer And Erosion Due To Crohn Disease

Granulomatous Enteritis
Appendix Cancer

Appendiceal Neoplasms

Cancer Of The Appendix

Malignant Neoplasm Of Appendix Vermiformis

Malignant Tumor Of Appendix

Malignant Tumor Of The Appendix

Malignant Neoplasm Of Appendix

Carcinoma Of The Appendix
Appendix Disease

Disorder Of Appendix
Gastric Cancer

Stomach Cancer

Gastric Carcinoma

Stomach Carcinoma

Gastric Cancer, Somatic

Gastric Neoplasm

Carcinoma Of Stomach

Stomach Neoplasms

Malignant Neoplasm Of Stomach

Gastric Cancer Risk After H. Pylori Infection

Cancer Of The Stomach

Adult Stomach Cancer

Adult Stomach Carcinoma

GASC

Gastric Cancer Intestinal

Gastric Cancers

Gastric Carcinomas

Cancer, Gastric

Stomach Neoplasm

Malignant Neoplasm Of Body Of Stomach

Malignant Tumor Of Lesser Curve Of Stomach

Gastrocarcinoma Of Unspecified Site

Leather Bottle Stomach

Carcinoma Of Fundus Of Stomach

Cancer Of Fundus Of Stomach

Primary Malignant Neoplasm Of Body Of Stomach

Cancer Of Body Of Stomach

Primary Malignant Neoplasm Of Pyloric Antrum

Pyloric Antrum Cancer

Malignant Tumour Of Stomach
Colorectal Cancer

Colon Cancer

Colorectal Carcinoma

Colon Carcinoma

Colorectal Cancer, Susceptibility To

Carcinoma Of Colon

CRC

Colorectal Cancer With Chromosomal Instability, Somatic

Colon Cancer, Somatic

Colon Cancer, Susceptibility To

Colonic Neoplasms

Colorectal Neoplasms

Colorectal Cancer, Somatic

Colon Cancer, Advanced, Somatic

Colonic Carcinoma

Colorectal Carcinomas

Colon Cancers

Colorectal Cancers

Cancer, Colorectal, Somatic

Cancer, Colon

Cancer, Colorectal, Susceptibility To

Colorectal Neoplasm

Colonic Neoplasm

Malignant Tumor Of Colon
Inflammatory Bowel Disease

Inflammatory Bowel Diseases

Bowel Disease, Inflammatory
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11822 REG4 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus REG4 RGD RGD:1303341
Mus musculus REG4 MGD MGI:1914959
Bos taurus REG4 VGNC VGNC:55669
Others REG4 NCBI
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