2. Gene
  3. SPARCL1 - SPARC like 1 Gene

SPARCL1 - SPARC like 1 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：SPARC 样 1

种属: Homo sapiens

同用名: SC1; MAST9; PIG33; MAST 9

基因 ID: 8404 | 基因类型: protein coding

关于 SPARCL1

Cytogenetic location: 4q22.1 Genomic coordinates (GRCh38): 4:87,473,335-87,529,376 (from NCBI)

This gene has 10 transcripts (splice variants), 192 orthologues and 1 paralogue. Broad expression in brain (RPKM 777.2), endometrium (RPKM 500.6) and 20 other tissues.

功能概要

预测可启用钙离子结合活性；胶原结合活性；和细胞外基质结合活性。预计参与解剖结构的发展和突触组织的调节。位于细胞外空间。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable calcium ion binding activity; collagen binding activity; and extracellular matrix binding activity. Predicted to be involved in anatomical structure development and regulation of synapse organization. Located in extracellular space. [provided by Alliance of Genome Resources, Apr 2022]

SPARCL1 基因产物(4)

mRNA Protein Name
NM_001128310.3 NP_001121782.1 SPARC-like protein 1 isoform 1 precursor
NM_001291976.2 NP_001278905.1 SPARC-like protein 1 isoform 2
NM_001291977.2 NP_001278906.1 SPARC-like protein 1 isoform 2
NM_004684.6 NP_004675.3 SPARC-like protein 1 isoform 1 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
20926826 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

SPARCL1 蛋白结构

FOLN

FOLN: Follistatin/Osteonectin-like EGF domain (433 - 454)

Kazal_1

Kazal_1: Kazal-type serine protease inhibitor domain (456 - 509)

SPARC_Ca_bdg

SPARC_Ca_bdg: Secreted protein acidic and rich in cysteine Ca binding region (513 - 650)

  • 0
  • 200
  • 400
  • 600
  • 664 a.a.
蛋白主名 其他名称

SPARC-like protein 1

SPARC-like 1 (hevin)

SPARCL1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
SPARCL1 Q14515 MYOC Homo sapiens Q99972
ELISA
20926826
种属内
SPARCL1 Q14515 MYOC Homo sapiens Q99972
Y2H
20926826
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Pancreatic Cancer

Pancreatic Carcinoma

Carcinoma Of Pancreas

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Cancer Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS13632 SPARCL1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus SPARCL1 RGD RGD:2531
Felis catus SPARCL1 VGNC VGNC:65602
Bos taurus SPARCL1 VGNC VGNC:35172
Macaca mulatta SPARCL1 VGNC VGNC:77855
Mus musculus SPARCL1 MGD MGI:108110
Others SPARCL1 NCBI
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