2. Gene
  3. UTP15 - UTP15 small subunit processome component Gene

UTP15 - UTP15 small subunit processome component Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：UTP15 小亚基加工组组件

种属: Homo sapiens

同用名: NET21

基因 ID: 84135 | 基因类型: protein coding

关于 UTP15

Cytogenetic location: 5q13.2 Genomic coordinates (GRCh38): 5:73,565,741-73,583,380 (from NCBI)

This gene has 8 transcripts (splice variants) and 203 orthologues. Ubiquitous expression in bone marrow (RPKM 3.2), thyroid (RPKM 2.7) and 25 other tissues.

功能概要

启用 RNA 结合活性。参与 rRNA 加工的正调控和 RNA 聚合酶 I 转录的正调控。位于内质网和纤维中心。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Involved in positive regulation of rRNA processing and positive regulation of transcription by RNA polymerase I. Located in endoplasmic reticulum and fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

UTP15 基因产物(3)

mRNA Protein Name
NM_001284430.1 NP_001271359.1 U3 small nucleolar RNA-associated protein 15 homolog isoform 2
NM_001284431.1 NP_001271360.1 U3 small nucleolar RNA-associated protein 15 homolog isoform 3
NM_032175.4 NP_115551.2 U3 small nucleolar RNA-associated protein 15 homolog isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22916032 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of rRNA processing IMP
IMP: 通过突变表型推断
17699751 GOA
involved in positive regulation of transcription by RNA polymerase I IMP
IMP: 通过突变表型推断
17699751 GOA
involved in ribosomal small subunit biogenesis IDA
IDA: 通过直接分析推断
34516797 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in fibrillar center IDA
IDA: 通过直接分析推断
24219289 GOA
located in nucleolus IDA
IDA: 通过直接分析推断
24219289 GOA
part of small-subunit processome IDA
IDA: 通过直接分析推断
34516797 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

UTP15 蛋白结构

WD40

WD40: WD domain, G-beta repeat (71 - 108)

WD40

WD40: WD domain, G-beta repeat (114 - 150)

WD40

WD40: WD domain, G-beta repeat (156 - 193)

WD40

WD40: WD domain, G-beta repeat (204 - 233)

WD40

WD40: WD domain, G-beta repeat (239 - 276)

UTP15_C

UTP15_C: UTP15 C terminal (340 - 490)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 518 a.a.
蛋白主名 其他名称

U3 small nucleolar RNA-associated protein 15 homolog

Src-associated protein SAW

关联疾病

疾病名称 别名
Branchiooculofacial Syndrome

Branchio-Oculo-Facial Syndrome

BOFS

Bof Syndrome

Hemangiomatous Branchial Clefts-Lip Pseudocleft Syndrome

Lip Pseudocleft-Hemangiomatous Branchial Cyst Syndrome

Branchial Clefts With Characteristic Facies, Growth Retardation, Imperforate Nasolacrimal Duct, And Premature Aging

Branchial Clefts With Characteristic Facies Growth Retardation Imperforate Nasolacrimal Duct And Premature Aging

Bofs Syndrome

Lip Pseudocleft-Hemagiomatous Branchial Cyst Syndrome
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (2)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-107372S4 Uridine triphosphate-15N2 dilithium ≥98.0% 否
HY-RS15576 UTP15 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta UTP15 VGNC VGNC:79539
Canis familiaris UTP15 VGNC VGNC:48209
Rattus norvegicus UTP15 RGD RGD:1310992
Bos taurus UTP15 VGNC VGNC:36742
Mus musculus UTP15 MGD MGI:2145443
Felis catus UTP15 VGNC VGNC:66902
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z