1. Gene
  2. NEURL4 - neuralized E3 ubiquitin protein ligase 4 Gene

NEURL4 - neuralized E3 ubiquitin protein ligase 4 Gene

中文名称:神经化 E3 泛素蛋白连接酶 4

种属: Homo sapiens

基因 ID: 84461 | 基因类型: protein coding

关于 NEURL4

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:7,315,628-7,329,335 (from NCBI)

This gene has 14 transcripts (splice variants), 1 gene allele, 182 orthologues and 3 paralogues. Ubiquitous expression in brain (RPKM 8.3), testis (RPKM 8.0) and 25 other tissues.

功能概要

预测由该基因编码的蛋白质,它包括由两个可变剪接的转录物变体产生的两种同种型。[RefSeq 提供,2008 年 7 月]

The protein encoded by this gene is predicted and it includes two isoforms resulting from two alternatively spliced transcript variants. [provided by RefSeq, Jul 2008]

NEURL4 基因产物(2)

mRNA Protein Name
NM_001005408.2 NP_001005408.1 neuralized-like protein 4 isoform 2
NM_032442.3 NP_115818.2 neuralized-like protein 4 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22441691 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

NEURL4 蛋白结构

Neuralized

Neuralized: Neuralized (44 - 111)

Neuralized

Neuralized: Neuralized (318 - 387)

Neuralized

Neuralized: Neuralized (521 - 590)

Neuralized

Neuralized: Neuralized (717 - 786)

Neuralized

Neuralized: Neuralized (915 - 980)

Neuralized

Neuralized: Neuralized (1132 - 1198)

  • 0
  • 300
  • 600
  • 900
  • 1200
  • 1562 a.a.
蛋白主名 其他名称

neuralized-like protein 4

neuralized homolog 4

NEURL4 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra NEURL4 Q96JN8 CCP110 Homo sapiens O43303
Pull Down
22441691
Intra NEURL4 Q96JN8 CCP110 Homo sapiens O43303
Anti Bait CoIP
22441691
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Retinitis Pigmentosa 75

RP75

Retinitis Pigmentosa, Type 75

Angelman Syndrome

AS

Happy Puppet Syndrome

Happy Puppet Syndrome, Formerly

Puppetlike Syndrome

Dyschromatosis Universalis Hereditaria

Duh

Atrophic Rhinitis

Rhinitis, Atrophic

Ozena

Rhinitis Sicca

Dry Rhinitis

Ozaena

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus NEURL4 VGNC VGNC:54462
Macaca mulatta NEURL4 VGNC VGNC:82197
Mus musculus NEURL4 MGD MGI:1921092
Rattus norvegicus NEURL4 RGD RGD:1308056
Felis catus NEURL4 VGNC VGNC:99289