2. Gene
  3. HINT2 - histidine triad nucleotide binding protein 2 Gene

HINT2 - histidine triad nucleotide binding protein 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：组氨酸三联体核苷酸结合蛋白 2

种属: Homo sapiens

同用名: HIT-17

基因 ID: 84681 | 基因类型: protein coding

关于 HINT2

Cytogenetic location: 9p13.3 Genomic coordinates (GRCh38): 9:35,812,960-35,815,479 (from NCBI)

This gene has 7 transcripts (splice variants), 192 orthologues and 2 paralogues. Ubiquitous expression in kidney (RPKM 37.3), fat (RPKM 32.0) and 25 other tissues.

功能概要

组氨酸三联体蛋白，如 HINT2，是核苷酸水解酶和转移酶，作用于核糖核苷酸的α-磷酸盐 (Brenner，2002 [PubMed 12119013]) 。[OMIM 提供，2008 年 3 月]

Histidine triad proteins, such as HINT2, are nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides (Brenner, 2002 [PubMed 12119013]).[supplied by OMIM, Mar 2008]

HINT2 基因产物(1)

mRNA Protein Name
NM_032593.3 NP_115982.1 adenosine 5'-monophosphoramidase HINT2 precursor
基因本体论
  • 分子功能
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables adenosine 5'-monophosphoramidase activity IDA
IDA: 通过直接分析推断
16762638 GOA
enables protein binding IPI
IPI: 通过物理相互作用推断
35156780 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
16762638 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

HINT2 蛋白结构

HIT

HIT: HIT domain (64 - 157)

  • 0
  • 100
  • 163 a.a.
蛋白主名 其他名称

adenosine 5'-monophosphoramidase HINT2

HINT-2

HINT2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
HINT2 Q9BX68 CFTR Homo sapiens P13569
Ub Reconstruction
35156780
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Ocular Melanoma

Intraocular Melanoma

Uveal Melanoma

Eye Melanoma

Melanoma Of Eye

Melanoma Of The Uvea

Malignant Melanoma Of Eye
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS06177 HINT2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta HINT2 VGNC VGNC:73411
Mus musculus HINT2 MGD MGI:1916167
Rattus norvegicus HINT2 RGD RGD:1308910
Canis familiaris HINT2 VGNC VGNC:49721
Felis catus HINT2 VGNC VGNC:62817
Bos taurus HINT2 VGNC VGNC:29855
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