GPAT3 - glycerol-3-phosphate acyltransferase 3 Gene

中文名称：3-磷酸甘油酰基转移酶 3

种属: Homo sapiens

同用名: MAG1; AGPAT8; AGPAT9; AGPAT10; AGPAT 10; HMFN0839; LPAAT-theta

基因 ID: 84803 | 基因类型: protein coding

关于 GPAT3

Cytogenetic location: 4q21.23 Genomic coordinates (GRCh38): 4:83,535,587-83,605,875 (from NCBI)

This gene has 8 transcripts (splice variants), 144 orthologues and 4 paralogues. Broad expression in kidney (RPKM 23.1), duodenum (RPKM 10.2) and 14 other tissues.

功能概要

该基因编码溶血磷脂酸酰基转移酶蛋白家族的一个成员。所编码的蛋白质是一种酶，可在三酰甘油的合成中催化甘油-3-磷酸转化为溶血磷脂酸。已经鉴定出编码相同蛋白质的多个可变剪接变体。[RefSeq 提供，2012 年 1 月]

This gene encodes a member of the lysophosphatidic acid Acyltransferase protein family. The encoded protein is an Enzyme which catalyzes the conversion of glycerol-3-phosphate to lysophosphatidic acid in the synthesis of triacylglycerol. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jan 2012]

GPAT3 基因产物(3)

mRNA	Protein	Name
NM_001256421.1	NP_001243350.1	glycerol-3-phosphate acyltransferase 3
NM_001256422.1	NP_001243351.1	glycerol-3-phosphate acyltransferase 3
NM_032717.5	NP_116106.2	glycerol-3-phosphate acyltransferase 3

基因本体论

分子功能
生物过程
细胞组分

分子功能 GO 注释	逻辑证据	参考文献	来源
enables 1-acylglycerol-3-phosphate O-acyltransferase activity	IDA IDA: 通过直接分析推断	19318427	GOA
NOT enables glycerol-3-phosphate O-acyltransferase activity	IDA IDA: 通过直接分析推断	19318427	GOA
enables glycerol-3-phosphate O-acyltransferase activity	IDA IDA: 通过直接分析推断	17170135	GOA

生物过程 GO 注释	逻辑证据	参考文献	来源
involved in regulation of TOR signaling	IDA IDA: 通过直接分析推断	17002884	GOA
involved in triglyceride biosynthetic process	IDA IDA: 通过直接分析推断	17170135	GOA

细胞组分 GO 注释	逻辑证据	参考文献	来源
located in endoplasmic reticulum	IDA IDA: 通过直接分析推断	17170135	GOA
located in endoplasmic reticulum membrane	IDA IDA: 通过直接分析推断	17002884	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GPAT3 蛋白结构

Acyltransferase

0
100
200
300
400
434 a.a.

蛋白主名

其他名称

glycerol-3-phosphate acyltransferase 3

1-AGP acyltransferase 9

关联疾病

疾病名称

别名

Congenital Generalized Lipodystrophy

Berardinelli-Seip Congenital Lipodystrophy	Berardinelli-Seip Syndrome
Brunzell Syndrome	Bscl
Generalized Lipodystrophy	Lipodystrophy, Congenital Generalized
Seip Syndrome	Total Lipodystrophy
Cgl	Lipoatrophic Diabetes
Lipodystrophy, Generalized, Congenital	Familial Generalized Lipodystrophy
Congenital Generalized Lipodystrophy Type 2	Lipoatrophic Diabetes Mellitus
Familial Partial Lipodystrophy, Type 2

Lipodystrophy, Congenital Generalized, Type 2

Congenital Generalized Lipodystrophy Type 2	CGL2
Berardinelli-Seip Congenital Lipodystrophy Type 2	Berardinelli-Seip Syndrome
Brunzell Syndrome Bscl2-Related	Total Lipodystrophy And Acromegaloid Gigantism
Berardinelli-Seip Congenital Lipodystrophy, Type 2	Seip Syndrome
Berardinelli Syndrome	Lipodystrophy, Total, And Acromegaloid Gigantism
Lipoatrophic Diabetes, Congenital	Lipodystrophy, Berardinelli-Seip Congenital, Type 2
Brunzell Syndrome, Bscl2-Related	Congenital Lipoatrophic Diabetes
Congenital Generalized Lipodystrophy 2	Lipoatrophic Diabetes
Lipodystrophy Berardinelli Type	Familial Generalized Lipodystrophy
Lipoatrophic Diabetes Mellitus	Familial Partial Lipodystrophy, Type 2

Complete Generalized Lipodystrophy

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS05617	GPAT3 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Bos taurus	GPAT3	VGNC	VGNC:29513
Canis familiaris	GPAT3	VGNC	VGNC:41363
Felis catus	GPAT3	VGNC	VGNC:62654
Macaca mulatta	GPAT3	VGNC	VGNC:106586
Rattus norvegicus	GPAT3	RGD	RGD:1565703
Mus musculus	GPAT3	MGD	MGI:3603816

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

GPAT3 - glycerol-3-phosphate acyltransferase 3 Gene

关于 GPAT3

功能概要

GPAT3 基因产物(3)

GPAT3 蛋白结构

关联疾病

直系同源

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GPAT3 - glycerol-3-phosphate acyltransferase 3 Gene

关于 GPAT3

功能概要

GPAT3 基因产物(3)

GPAT3 蛋白结构

关联疾病

相关产品

直系同源

热门区域

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C

F

G

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J

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