2. Gene
  3. ARHGEF39 - Rho guanine nucleotide exchange factor 39 Gene

ARHGEF39 - Rho guanine nucleotide exchange factor 39 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：Rho 鸟嘌呤核苷酸交换因子 39

种属: Homo sapiens

同用名: C9orf100

基因 ID: 84904 | 基因类型: protein coding

关于 ARHGEF39

This gene has 6 transcripts (splice variants), 202 orthologues and 10 paralogues. Ubiquitous expression in fat (RPKM 7.7), adrenal (RPKM 3.6) and 25 other tissues.

功能概要

预测可启用胍基核苷酸交换因子活性。参与细胞迁移的正向调节。位于质膜。 [由基因组资源联盟提供，2022 年 4 月]

Predicted to enable guanyl-nucleotide exchange factor activity. Involved in positive regulation of cell migration. Located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

ARHGEF39 基因产物(1)

mRNA Protein Name
NM_032818.3 NP_116207.2 rho guanine nucleotide exchange factor 39
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in positive regulation of cell migration IDA
IDA: 通过直接分析推断
22327280 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in plasma membrane IDA
IDA: 通过直接分析推断
22327280 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ARHGEF39 蛋白结构

RhoGEF

RhoGEF: RhoGEF domain (27 - 194)

  • 0
  • 100
  • 200
  • 300
  • 335 a.a.
蛋白主名 其他名称

rho guanine nucleotide exchange factor 39

Rho guanine nucleotide exchange factor (GEF) 39

ARHGEF39 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
Intra ARHGEF39 Q8N4T4 TYSND1 Homo sapiens Q2T9J0
Anti Tag CoIP
33961781
Intra ARHGEF39 Q8N4T4 CALCOCO2 Homo sapiens Q13137
Y2H Array
31515488
Intra ARHGEF39 Q8N4T4 CALCOCO2 Homo sapiens Q13137
Y2H Prey Pooling
25416956
Intra ARHGEF39 Q8N4T4 CALCOCO2 Homo sapiens Q13137
Validated Y2H
25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称 别名
Hepatocellular Carcinoma

Liver Cancer

Primary Liver Cancer

HCC

Hepatoma

Malignant Neoplasm Of Liver

Liver Neoplasms

Cancer, Hepatocellular

Liver Cell Carcinoma

Lcc

Hepatoblastoma, Somatic

Hepatic Cancer

Primary Malignant Neoplasm Of Liver

Rare Tumor Of Liver And Intrahepatic Biliary Tract

Hepatocellular Carcinoma, Somatic

Hepatocellular Carcinoma, Childhood Type, Somatic

Hepatocellular Cancer, Somatic

Ca Liver - Primary

Hepatic Neoplasm

Malignant Hepato-Biliary Neoplasm

Malignant Neoplasm Of Liver, Not Specified As Primary Or Secondary

Malignant Neoplasm Of Liver, Primary

Malignant Tumor Of Liver

Neoplasm Of Liver

Non-Resectable Primary Hepatic Malignant Neoplasm

Resectable Malignant Neoplasm Of Liver

Resectable Malignant Neoplasm Of The Liver

Primary Liver Carcinoma

Primary Malignant Liver Neoplasm

Primary Cancer Of Liver

Primary Tumor Of The Liver

Rare Tumor Of Liver And Ibt

Hepatocellular Cancer

Neoplasm Of The Liver

Carcinoma, Hepatocellular

Hepatomas

Liver Neoplasm

Liver Carcinoma

Liver And Intrahepatic Biliary Tract Carcinoma

Malignant Hepatobiliary Neoplasm

Adult Primary Hepatocellular Carcinoma

Hepatoblastoma

Carcinoma Of Liver

Malignant Liver Tumour

Malignant Hepatic Tumour
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS00959 ARHGEF39 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ARHGEF39 RGD RGD:1310376
Macaca mulatta ARHGEF39 VGNC VGNC:69912
Felis catus ARHGEF39 VGNC VGNC:59907
Canis familiaris ARHGEF39 VGNC VGNC:38088
Mus musculus ARHGEF39 MGD MGI:3036286
Bos taurus ARHGEF39 VGNC VGNC:26117
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