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  2. ALKBH6 - alkB homolog 6 Gene

ALKBH6 - alkB homolog 6 Gene

中文名称:alkB 同系物 6

种属: Homo sapiens

同用名: ABH6

基因 ID: 84964 | 基因类型: protein coding

关于 ALKBH6

Cytogenetic location: 19q13.12 Genomic coordinates (GRCh38): 19:36,009,120-36,014,239 (from NCBI)

This gene has 19 transcripts (splice variants), 179 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 5.2), spleen (RPKM 4.9) and 25 other tissues.

功能概要

预测可启用双加氧酶活性和金属离子结合活性。位于粘着斑和核质内。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable dioxygenase activity and metal ion binding activity. Located in focal adhesion and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

ALKBH6 基因产物(5)

mRNA Protein Name
NM_001297701.2 NP_001284630.1 alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform 3
NM_001386055.1 NP_001372984.1 alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform 3
NM_001386056.1 NP_001372985.1 alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform 4
NM_032878.5 NP_116267.4 alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform 3
NM_198867.1 NP_942567.1 alpha-ketoglutarate-dependent dioxygenase alkB homolog 6 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
22948820 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

ALKBH6 蛋白结构

2OG-FeII_Oxy_2

2OG-FeII_Oxy_2: 2OG-Fe(II) oxygenase superfamily (73 - 224)

  • 0
  • 100
  • 200
  • 238 a.a.
蛋白主名 其他名称

alpha-ketoglutarate-dependent dioxygenase alkB homolog 6

alkB, alkylation repair homolog 6

关联疾病

疾病名称 别名
Noonan Syndrome 5

NS5

Noonan Syndrome, Type 5

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Canis familiaris ALKBH6 VGNC VGNC:37806
Mus musculus ALKBH6 MGD MGI:2142037
Rattus norvegicus ALKBH6 RGD RGD:1566318
Macaca mulatta ALKBH6 VGNC VGNC:69726
Bos taurus ALKBH6 VGNC VGNC:25837