2. Gene
  3. MMP23B - matrix metallopeptidase 23B Gene

MMP23B - matrix metallopeptidase 23B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：基质金属肽酶 23B

种属: Homo sapiens

同用名: MIFR; MMP22; MIFR-1; MMP23A

基因 ID: 8510 | 基因类型: protein coding

关于 MMP23B

Cytogenetic location: 1p36.33 Genomic coordinates (GRCh38): 1:1,632,173-1,634,654 (from NCBI)

This gene has 10 transcripts (splice variants), 186 orthologues, 23 paralogues and is associated with 1 phenotype. Broad expression in placenta (RPKM 4.1), prostate (RPKM 3.5) and 21 other tissues.

功能概要

该基因 (MMP23B) 编码基质金属蛋白酶 (MMP) 家族的一个成员，它是染色体 1p36.3 重复区域的一部分。基质金属蛋白酶 (MMP) 家族的蛋白质参与正常生理过程 (如胚胎发育、繁殖和组织重塑) 以及疾病过程 (如关节炎和转移) 中细胞外基质的分解。该基因属于复制区域的更多端粒拷贝。[RefSeq 提供，2008 年 7 月]

This gene (MMP23B) encodes a member of the matrix metalloproteinase (MMP) family, and it is part of a duplicated region of chromosome 1p36.3. Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. This gene belongs to the more telomeric copy of the duplicated region. [provided by RefSeq, Jul 2008]

MMP23B 基因产物(1)

mRNA Protein Name
NM_006983.2 NP_008914.1 matrix metalloproteinase-23 precursor
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables metalloendopeptidase activity IDA
IDA: 通过直接分析推断
9988691 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

MMP23B 蛋白结构

Peptidase_M10

Peptidase_M10: Matrixin (87 - 254)

ShK

ShK: ShK domain-like (255 - 289)

Ig_2

Ig_2: Immunoglobulin domain (306 - 388)

  • 0
  • 100
  • 200
  • 300
  • 390 a.a.
蛋白主名 其他名称

matrix metalloproteinase-23

MMP-21

关联疾病

疾病名称 别名
Chromosome 1p36 Deletion Syndrome

1p36 Deletion Syndrome

Deletion 1p36

Monosomy 1p36

Subtelomeric 1p36 Deletion

Monosomy 1p36 Syndrome

Distal Monosomy 1p36

Del(1)(P36)

Deletion 1pter

Monosomy 1pter
Primary Ciliary Dyskinesia

Immotile Cilia Syndrome

Kartagener Syndrome

Dextrocardia Bronchiectasis And Sinusitis

Pcd

Ciliary Motility Disorders

Ciliary Motility Disorder

Immotile Ciliary Syndrome

Ciliary Dyskinesia Primary

Ics

Polynesian Bronchiectasis

Dextrocardia-Bronchiectasis-Sinusitis Syndrome

Immotile Cilia Syndrome, Kartagener Type

Primary Ciliary Dyskinesia And Situs Inversus

Primary Ciliary Dyskinesia, Kartagener Type

Siewert Syndrome

Dyskinesia, Ciliary, Primary
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS08542 MMP23B Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Bos taurus MMP23B VGNC VGNC:53594
Felis catus MMP23B VGNC VGNC:82534
Rattus norvegicus MMP23B RGD RGD:620201
Macaca mulatta MMP23B VGNC VGNC:106408
Mus musculus MMP23B MGD MGI:1347361
Canis familiaris MMP23B VGNC VGNC:53425
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