1. Gene
  2. LBX2 - ladybird homeobox 2 Gene

LBX2 - ladybird homeobox 2 Gene

中文名称:瓢虫同源盒 2

种属: Homo sapiens

同用名: LP3727

基因 ID: 85474 | 基因类型: protein coding

关于 LBX2

Cytogenetic location: 2p13.1 Genomic coordinates (GRCh38): 2:74,497,517-74,503,316 (from NCBI)

This gene has 6 transcripts (splice variants), 322 orthologues and 1 paralogue. Biased expression in liver (RPKM 2.5), small intestine (RPKM 1.7) and 11 other tissues.

功能概要

启用序列特异性双链 DNA 结合活性。预计参与多个过程,包括肌肉细胞分化;原肠胚形成过程中收敛延伸的正调控;和非经典 Wnt 信号通路的正调控。预测是染色质的一部分。预计活跃于核心。 [由基因组资源联盟提供,2022 年 4 月]

Enables sequence-specific double-stranded DNA binding activity. Predicted to be involved in several processes, including muscle cell differentiation; positive regulation of convergent extension involved in gastrulation; and positive regulation of non-canonical Wnt signaling pathway. Predicted to be part of chromatin. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]

LBX2 基因产物(2)

mRNA Protein Name
NM_001009812.2 NP_001009812.1 transcription factor LBX2 isoform 2
NM_001282430.2 NP_001269359.1 transcription factor LBX2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32296183 GOA
enables sequence-specific double-stranded DNA binding IDA
IDA: 通过直接分析推断
28473536 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

LBX2 蛋白结构

Homeobox

Homeobox: Homeobox domain (86 - 142)

  • 0
  • 100
  • 198 a.a.
蛋白主名 其他名称

transcription factor LBX2

ladybird homeobox protein homolog 2

直系同源

种属 基因名 来源 基因 ID
Canis familiaris LBX2 VGNC VGNC:42604
Mus musculus LBX2 MGD MGI:1342288
Felis catus LBX2 VGNC VGNC:63202
Rattus norvegicus LBX2 RGD RGD:1561172
Bos taurus LBX2 VGNC VGNC:30806
Macaca mulatta LBX2 VGNC VGNC:84894