2. Gene
  3. RNASET2 - ribonuclease T2 Gene

RNASET2 - ribonuclease T2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：核糖核酸酶 T2

种属: Homo sapiens

同用名: RNASE6PL; bA514O12.3

基因 ID: 8635 | 基因类型: protein coding

关于 RNASET2

Cytogenetic location: 6q27 Genomic coordinates (GRCh38): 6:166,922,113-166,956,550 (from NCBI)

This gene has 22 transcripts (splice variants), 203 orthologues and is associated with 3 phenotypes. Broad expression in spleen (RPKM 93.0), colon (RPKM 39.0) and 24 other tissues.

功能概要

这种核糖核酸酶基因是胞外核糖核酸酶 Rh/T2/S-糖蛋白类的一个新成员。它是一个映射到 6q27 的单拷贝基因，6q27 是一个与人类恶性肿瘤和染色体重排相关的区域。[RefSeq 提供，2008 年 7 月]

This ribonuclease gene is a novel member of the Rh/T2/S-glycoprotein class of extracellular ribonucleases. It is a single copy gene that maps to 6q27, a region associated with human malignancies and chromosomal rearrangement. [provided by RefSeq, Jul 2008]

RNASET2 基因产物(1)

mRNA Protein Name
NM_003730.6 NP_003721.2 ribonuclease T2 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables RNA nuclease activity IDA
IDA: 通过直接分析推断
22735700 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in RNA catabolic process IDA
IDA: 通过直接分析推断
22735700 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in endoplasmic reticulum lumen IDA
IDA: 通过直接分析推断
16620762 GOA
located in extracellular space IDA
IDA: 通过直接分析推断
16620762 GOA
located in lysosome IDA
IDA: 通过直接分析推断
16620762 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

RNASET2 蛋白结构

Ribonuclease_T2

Ribonuclease_T2: Ribonuclease T2 family (35 - 214)

  • 0
  • 100
  • 200
  • 256 a.a.
蛋白主名 其他名称

ribonuclease T2

ribonuclease 6

重组 RNASET2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P71015 RNASET2 Protein, Human (HEK293, His) O00584 (D25-H256) ≥95%
HY-P76006 RNASET2 Protein, Human (sf9, His) O00584 (D25-H256) ≥95%

关联疾病

疾病名称 别名
Leukoencephalopathy, Cystic, Without Megalencephaly

Cystic Leukoencephalopathy Without Megalencephaly

Rnaset2-Deficient Cystic Leukoencephalopathy

Rnase T2-Deficient Leukoencephalopathy

Clwm

Leukoencephalopathy With Bilateral Anterior Temporal Lobe Cysts

Infantile-Onset Rnaset2 Deficient Cystic Leukoencephalopathy

Lbatc

LCWM
Pseudo-Torch Syndrome 1

Pseudo-Torch Syndrome

Band-Like Calcification With Simplified Gyration And Polymicrogyria

Blcpmg

PTORCH1

Baraitser-Brett-Piesowicz Syndrome

Baraitser-Reardon Syndrome

Bilateral Band-Like Calcification With Polymicrogyria

Blc-Pmg

Microcephaly-Intracranial Calcification-Intellectual Disability Syndrome

Congenital Intrauterine Infection-Like Syndrome

Baraitser Brett Piesowicz Syndrome

Microcephaly - Intracranial Calcification - Intellectual Disability
Megalencephaly

Macroencephaly

Macrencephaly
Aicardi-Goutieres Syndrome

Aicardi Goutieres Syndrome

Cree Encephalitis

Aicardi-Goutières Syndrome

Encephalopathy With Basal Ganglia Calcification

Ags

Encephalopathy With Intracranial Calcification And Chronic Lymphocytosis Of Cerebrospinal Fluid

Pseudotoxoplasmosis Syndrome

Encephalopathy, Familial Infantile, With Calcification Of Basal Ganglia And Chronic Cerebrospinal Fluid Lymphocytosis

Familial Infantile Encephalopathy With Intracranial Calcification And Chronic Cerebrospinal Fluid Lymphocytosis

Aicardi-Goutieres Syndrome 1
Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary
Microcephaly

Microencephaly

Microcephalus

Microcephalic

Nanocephaly

Congenital Microcephaly

Brain Hypoplasia

Brain Nondevelopment

Cephalic Hypoplasia

Undeveloped Cerebrum

Undeveloped Brain

Micrencephalon

Micrencephaly
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS12030 RNASET2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus RNASET2 VGNC VGNC:102504
Rattus norvegicus RNASET2 RGD RGD:1309918
Macaca mulatta RNASET2 VGNC VGNC:99439
Others RNASET2 NCBI
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