1. Gene
  2. DCAF15 - DDB1 and CUL4 associated factor 15 Gene

DCAF15 - DDB1 and CUL4 associated factor 15 Gene

中文名称:DDB1 和 CUL4 相关因子 15

种属: Homo sapiens

同用名: C19orf72

基因 ID: 90379 | 基因类型: protein coding

关于 DCAF15

Cytogenetic location: 19p13.12 Genomic coordinates (GRCh38): 19:13,952,509-13,961,449 (from NCBI)

This gene has 6 transcripts (splice variants), 1 gene allele and 177 orthologues. Broad expression in testis (RPKM 20.9), bone marrow (RPKM 11.3) and 24 other tissues.

功能概要

启用小分子结合活性。参与蛋白质多聚泛素化和自然杀伤细胞活化的调节。 Cul4-RING E3 泛素连接酶复合物的一部分。 [由基因组资源联盟提供,2022 年 4 月]

Enables small molecule binding activity. Involved in protein polyubiquitination and regulation of natural killer cell activation. Part of Cul4-RING E3 ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

DCAF15 基因产物(9)

mRNA Protein Name
NM_001393637.1 NP_001380566.1 DDB1- and CUL4-associated factor 15 isoform 2
NM_001393638.1 NP_001380567.1 DDB1- and CUL4-associated factor 15 isoform 3
NM_001393639.1 NP_001380568.1 DDB1- and CUL4-associated factor 15 isoform 4
NM_001393640.1 NP_001380569.1 DDB1- and CUL4-associated factor 15 isoform 5
NM_001393641.1 NP_001380570.1 DDB1- and CUL4-associated factor 15 isoform 6
NM_001393642.1 NP_001380571.1 DDB1- and CUL4-associated factor 15 isoform 7
NM_001393643.1 NP_001380572.1 DDB1- and CUL4-associated factor 15 isoform 8
NM_001393644.1 NP_001380573.1 DDB1- and CUL4-associated factor 15 isoform 9
NM_138353.4 NP_612362.2 DDB1- and CUL4-associated factor 15 isoform 1
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
16949367 GOA
enables small molecule binding IPI
IPI: 通过物理相互作用推断
28302793 GOA
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in protein polyubiquitination IDA
IDA: 通过直接分析推断
28302793 GOA
involved in regulation of natural killer cell activation IMP
IMP: 通过突变表型推断
31452512 GOA
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of Cul4-RING E3 ubiquitin ligase complex IDA
IDA: 通过直接分析推断
16949367 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

DCAF15 蛋白结构

DCAF15_WD40

DCAF15_WD40: DDB1-and CUL4-substrate receptor 15, WD repeat (47 - 260)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600 a.a.
蛋白主名 其他名称

DDB1- and CUL4-associated factor 15

直系同源

种属 基因名 来源 基因 ID
Macaca mulatta DCAF15 VGNC VGNC:71706
Rattus norvegicus DCAF15 RGD RGD:1304881
Mus musculus DCAF15 MGD MGI:2684420
Canis familiaris DCAF15 VGNC VGNC:39792
Felis catus DCAF15 VGNC VGNC:61356
Bos taurus DCAF15 VGNC VGNC:27902
Others DCAF15 NCBI