ANGPTL1 - angiopoietin like 1 Gene

中文名称：血管生成素样 1

种属: Homo sapiens

同用名: ANG3; ARP1; AngY; ANGPT3; UNQ162; dJ595C2.2

关于 ANGPTL1

功能概要

血管生成素是血管内皮生长因子家族的成员，并且是唯一已知的主要对血管内皮具有特异性的生长因子。 Angiopoietin-1、angiopoietin-2 和 Angiopoietin-4 参与血管的形成。由该基因编码的蛋白质是血管生成素家族的另一个成员，广泛表达于成人组织中，其 mRNA 水平在高度血管化的组织中最高。发现该蛋白是一种分泌蛋白，在体外不作为内皮细胞有丝分裂原。[RefSeq 提供，2008 年 7 月]

Angiopoietins are members of the vascular endothelial growth factor family and the only known growth factors largely specific for vascular endothelium. Angiopoietin-1, angiopoietin-2, and Angiopoietin-4 participate in the formation of blood vessels. The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues. This protein was found to be a secretory protein that does not act as an endothelial cell mitogen in vitro. [provided by RefSeq, Jul 2008]