1. Gene
  2. IGFN1 - immunoglobulin like and fibronectin type III domain containing 1 Gene

IGFN1 - immunoglobulin like and fibronectin type III domain containing 1 Gene

中文名称:含免疫球蛋白样和纤连蛋白 III 型域 1

种属: Homo sapiens

同用名: EEF1A2BP1

基因 ID: 91156 | 基因类型: protein coding

关于 IGFN1

Cytogenetic location: 1q32.1 Genomic coordinates (GRCh38): 1:201,190,824-201,228,952 (from NCBI)

This gene has 5 transcripts (splice variants), 141 orthologues and 9 paralogues. Biased expression in endometrium (RPKM 9.4), testis (RPKM 3.4) and 5 other tissues.

功能概要

预计通过质膜粘附分子参与嗜同细胞粘附;视网膜层形成;和突触组装。预测位于 Z 盘和核内。预测在突触中活跃。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to be involved in homophilic cell adhesion via plasma membrane adhesion molecules; retina layer formation; and synapse assembly. Predicted to be located in Z disc and nucleus. Predicted to be active in synapse. [provided by Alliance of Genome Resources, Apr 2022]

IGFN1 基因产物(2)

mRNA Protein Name
NM_001164586.2 NP_001158058.1 immunoglobulin-like and fibronectin type III domain-containing protein 1 isoform 1
NM_001367841.1 NP_001354770.1 immunoglobulin-like and fibronectin type III domain-containing protein 1 isoform 2
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25416956 GOA
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断

IGFN1 蛋白结构

I-set

I-set: Immunoglobulin I-set domain (74 - 156)

I-set

I-set: Immunoglobulin I-set domain (166 - 257)

fn3

fn3: Fibronectin type III domain (268 - 346)

fn3

fn3: Fibronectin type III domain (363 - 445)

fn3

fn3: Fibronectin type III domain (465 - 548)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 608 a.a.
蛋白主名 其他名称

immunoglobulin-like and fibronectin type III domain-containing protein 1

EEF1A2-binding protein 1

IGFN1 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
IGFN1 Q86VF2 MEOX2 Homo sapiens P50222 25416956
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus IGFN1 RGD RGD:1565384
Felis catus IGFN1 VGNC VGNC:62891
Bos taurus IGFN1 VGNC VGNC:59401
Macaca mulatta IGFN1 VGNC VGNC:99976
Mus musculus IGFN1 MGD MGI:3045352