1. Gene
  2. TIMD4 - T cell immunoglobulin and mucin domain containing 4 Gene

TIMD4 - T cell immunoglobulin and mucin domain containing 4 Gene

中文名称:含 T 细胞免疫球蛋白和粘蛋白结构域 4

种属: Homo sapiens

同用名: TIM4; SMUCKLER

基因 ID: 91937 | 基因类型: protein coding

关于 TIMD4

Cytogenetic location: 5q33.3 Genomic coordinates (GRCh38): 5:156,919,292-156,963,226 (from NCBI)

This gene has 3 transcripts (splice variants), 162 orthologues and 3 paralogues. Biased expression in lymph node (RPKM 8.4), testis (RPKM 2.6) and 5 other tissues.

功能概要

预测启用磷脂酰丝氨酸结合活性。预测作用于凋亡细胞清除的上游或内部。预计是膜的组成部分。 [由基因组资源联盟提供,2022 年 4 月]

Predicted to enable phosphatidylserine binding activity. Predicted to act upstream of or within apoptotic cell clearance. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

TIMD4 基因产物(2)

mRNA Protein Name
NM_001146726.2 NP_001140198.1 T-cell immunoglobulin and mucin domain-containing protein 4 isoform 2 precursor
NM_138379.3 NP_612388.2 T-cell immunoglobulin and mucin domain-containing protein 4 isoform 1 precursor

TIMD4 蛋白结构

V-set

V-set: Immunoglobulin V-set domain (22 - 117)

  • 0
  • 100
  • 200
  • 300
  • 378 a.a.
蛋白主名 其他名称

T-cell immunoglobulin and mucin domain-containing protein 4

T-cell immunoglobulin mucin receptor 4

重组 TIMD4 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70976 TIM-4/TIMD-4 Protein, Human (HEK293, His) AAH08988.1 (E25-L315) ≥95%
HY-P75552 TIM-4/TIMD-4 Protein, Human (Biotinylated, HEK293, His) AAH08988.1 (E25-L315) ≥95%

关联疾病

疾病名称 别名
Histiocytic Sarcoma

Malignant Histiocytosis

Langerhans Cell Sarcoma

Malignant Langerhans Cell Sarcoma

Malaria

Malaria, Susceptibility To

Malaria, Resistance To

Malaria, Cerebral

Cerebral Malaria

Malaria, Severe, Susceptibility To

Malaria, Severe, Resistance To

Malaria, Cerebral, Susceptibility To

Induced Malaria

Malaria, Vivax, Protection Against

Malaria, Severe

Malaria, Cerebral, Reduced Risk Of

Malaria, Protection Against

Resistance To Malaria Due To G6pd Deficiency

Malaria Due To G6pd Deficiency

Malarial Encephalitis

CM

Malaria Cerebral

Susceptibility To Malaria

Acute Pernicious Fever

Aestivo-Autumnal Fever

Aestivo Autumnal Malaria

Chagres Fever

Continued Malaria Fever

Estivo-Autumnal Fever

Estivo-Autumnal Malaria

Estivo-Autumnal Malarial Fever

Falciparum Fever

Malignant Tertian Fever

Malignant Tertian Malaria

Pernicious Intermittent Fever

Pernicious Malaria

Quotidian Malaria

Subtertian Fever

Subtertian Malaria Fever

Subtertian Malignant Tertian Malaria

Tropical Malaria

Algid Malaria

Bilious Haemoglobinuric Fever

Black Water Fever

Blackwater Fever

Malarial Blackwater Fever

Severe Malarial Falciparum

West African Fever

Malarial Haematinuria

Haemoglobinuric Fever

Haemoglobinuric Malaria

Severe Plasmodium Falciparum Malaria

Malarial Haemoglobinuria

Malarial Haematuria

Falciparum Malaria [Malignant Tertian]

Malaria Tropica

Malarial Shock

Chagres Virus Disease

Malignant Malaria

Mtm - [Malignant Tertian Malaria]

Tm -[Malignant Tertian Malaria]

Panama Fever

St - [Subtertian Malaria]

Malarial Quotidian

Benign Tertian Malaria

Tertian Ague

Vivax Fever

Plasmodium Vivax Malaria Nos

Btm - [Benign Tertian Malaria]

Bt - [Benign Tertian Malaria]

Vivax Malaria

Benign Tertian Vivax Malaria

Tertian Malaria

Quartan Malaria

Quartan Ague

Quartan Fever

Plasmodium Malariae Malaria Nos

Quartan Malarial

Malaria By Plasmodium Malariae

Malariae Malaria

Ovale Tertian Malaria

Plasmodium Ovale Fever

Malaria Fever By Plasmodium Ovale

Ovale Malaria

Malaria By Plasmodium Ovale

Malarial Ovale

Marsh Fever

Remittent Congestive Fever

Coastal Fever

Remittent Gastric Fever

Miasmatic Fever

Congestive Remittent Fever

Intermittent Fever

Jungle Fever

Paludism

Cameroon Fever

Ague

Corsican Fever

Intermittent Bilious Fever

Disease Due To Plasmodiidae

Malarial Fever

Plasmodiosis

Remittent Fever

Roman Fever

Malaria Fever Nos

Malaria Nos

Paludal Fever

Clinically Diagnosed Malaria

Clinically Diagnosed Malaria Without Parasitological Confirmation

Congestive Fever

Malarial Cachexia

Marsh Cachexia

Paludal Cachexia

Recurrent Malaria

Remittent Malaria

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Felis catus TIMD4 VGNC VGNC:102345
Bos taurus TIMD4 VGNC VGNC:55313
Rattus norvegicus TIMD4 RGD RGD:1564516
Mus musculus TIMD4 MGD MGI:2445125
Macaca mulatta TIMD4 VGNC VGNC:79477
Canis familiaris TIMD4 VGNC VGNC:51911
Macaca fascicularis TIMD4 NCBI NCBI:102140672
Others TIMD4 NCBI