2. Gene
  3. GLP2R - glucagon like peptide 2 receptor Gene

GLP2R - glucagon like peptide 2 receptor Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：胰高血糖素样肽 2 受体

种属: Homo sapiens

基因 ID: 9340 | 基因类型: protein coding

关于 GLP2R

Cytogenetic location: 17p13.1 Genomic coordinates (GRCh38): 17:9,825,924-9,892,099 (from NCBI)

This gene has 4 transcripts (splice variants), 205 orthologues and 42 paralogues. Biased expression in gall bladder (RPKM 4.7), small intestine (RPKM 2.6) and 8 other tissues.

功能概要

该基因编码与胰高血糖素受体密切相关的 G 蛋白偶联受体，并与胰高血糖素样肽 2 (GLP2) 结合。通过 GLP2 的信号刺激肠道生长并增加小肠绒毛高度，同时伴随着隐窝细胞增殖增加和肠细胞凋亡减少。[RefSeq 提供，2014 年 12 月]

This gene encodes a G protein-coupled receptor that is closely related to the Glucagon Receptor and binds to glucagon-like peptide-2 (GLP2). Signalling through GLP2 stimulates intestinal growth and increases villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte Apoptosis. [provided by RefSeq, Dec 2014]

GLP2R 基因产物(1)

mRNA Protein Name
NM_004246.3 NP_004237.1 glucagon-like peptide 2 receptor

GLP2R 蛋白结构

HRM

HRM: Hormone receptor domain (95 - 151)

7tm_2

7tm_2: 7 transmembrane receptor (Secretin family) (176 - 432)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 553 a.a.
蛋白主名 其他名称

glucagon-like peptide 2 receptor

GLP-2 receptor

关联疾病

疾病名称 别名
Short Bowel Syndrome

Short Gut Syndrome

Acquired Short Bowel Syndrome

Secondary Short Bowel Syndrome

Short Bowel Nos
Ileus

Ileus Of Intestine
Chondrodysplasia, Blomstrand Type

Chondrodysplasia Blomstrand Type

BOCD

Blomstrand Lethal Chondrodysplasia

Blomstrand Lethal Osteochondrodysplasia

Blomstrand'S Lethal Chondrodysplasia

Blc

Blomstrand Chondrodysplasia

Blomstrand Osteochondrodysplasia
Mucositis

Inflammatory Disease Of Mucous Membrane

Gastrointestinal Mucositis
Isolated Growth Hormone Deficiency, Type Ib

Isolated Growth Hormone Deficiency Type Ib

IGHD1B

Ighd Ib

Growth Hormone Deficiency, Isolated, Type Ib

Congenital Ighd Type Ib

Congenital Isolated Gh Deficiency Type Ib

Congenital Isolated Growth Hormone Deficiency Type Ib

Dwarfism Of Sindh

Pituitary Dwarfism I

Isolated Growth Hormone Deficiency Type 1b

Ighd 1b

Growth Hormone Deficiency, Isolated, 1b
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Clinical Phase
生物活性分子 (3)
目录号 产品名 作用方式
纯度 Phase
HY-P2221B Glepaglutide acetate Agonist 99.92% Phase 3
HY-P2221 Glepaglutide Agonist / Phase 3
HY-P3291 Dapiglutide Agonist 99.40% Phase 2
Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS05491 GLP2R Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Felis catus GLP2R VGNC VGNC:62587
Canis familiaris GLP2R VGNC VGNC:41267
Bos taurus GLP2R VGNC VGNC:29411
Macaca mulatta GLP2R VGNC VGNC:73073
Mus musculus GLP2R MGD MGI:2136733
Rattus norvegicus GLP2R RGD RGD:620270
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z