1. Gene
  2. Cadm3 - cell adhesion molecule 3 Gene

Cadm3 - cell adhesion molecule 3 Gene

种属: Mus musculus

同用名: BIgR; Necl1; Tsll1; Igsf4b; Necl-1; SynCAM3

基因 ID: 94332 | 基因类型: protein coding

关于 Cadm3

功能概要

Enables protein homodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules and homophilic cell adhesion via plasma membrane adhesion molecules. Acts upstream of or within protein localization. Located in cell-cell junction and parallel fiber to Purkinje cell synapse. Is integral component of presynaptic membrane. Is expressed in several structures, including intestine; liver; nervous system; neural retina; and olfactory epithelium. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease. Orthologous to human CADM3 (cell adhesion molecule 3). [provided by Alliance of Genome Resources, Apr 2022]

Cadm3 基因产物(3)

mRNA Protein Name
NM_001412814.1 NP_001399743.1 cell adhesion molecule 3 isoform 1 precursor
NM_001412815.1 NP_001399744.1 cell adhesion molecule 3 isoform 2
NM_053199.4 NP_444429.1 cell adhesion molecule 3 isoform 3 precursor
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
15893517 MGI
enables protein homodimerization activity IPI
IPI: 通过物理相互作用推断
12826663 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules IDA
IDA: 通过直接分析推断
12826663 MGI
involved in homophilic cell adhesion via plasma membrane adhesion molecules IDA
IDA: 通过直接分析推断
12826663 MGI
acts upstream of or within protein localization IMP
IMP: 通过突变表型推断
15893517 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in cell-cell junction IDA
IDA: 通过直接分析推断
15893517 MGI
is active in parallel fiber to Purkinje cell synapse IDA
IDA: 通过直接分析推断
15741237 MGI
is active in presynaptic membrane IDA
IDA: 通过直接分析推断
15741237 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

cell adhesion molecule 3

TSLC1-like protein 1

immunoglobulin superfamily, member 4B

nectin-like protein 1

nectin-lke 1

synaptic cell adhesion molecule 3

重组 Cadm3 蛋白

目录号 产品名 蛋白编号 纯度
HY-P76756 CADM3 Protein, Mouse (HEK293, His) Q99N28 (N23-H328) ≥95%

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Cadm3 NCBI NCBI:57863
Macaca fascicularis Cadm3 NCBI NCBI:102129491
Rattus norvegicus Cadm3 NCBI NCBI:360882