2. Gene
  3. ENTPD2 - ectonucleoside triphosphate diphosphohydrolase 2 Gene

ENTPD2 - ectonucleoside triphosphate diphosphohydrolase 2 Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：外核苷三磷酸二磷酸水解酶 2

种属: Homo sapiens

同用名: CD39L1; NTPDase-2

基因 ID: 954 | 基因类型: protein coding

关于 ENTPD2

Cytogenetic location: 9q34.3 Genomic coordinates (GRCh38): 9:137,048,107-137,054,061 (from NCBI)

This gene has 4 transcripts (splice variants), 250 orthologues and 7 paralogues. Broad expression in duodenum (RPKM 4.7), prostate (RPKM 4.6) and 17 other tissues.

功能概要

该基因编码的蛋白质是外核苷三磷酸二磷酸水解酶家族 (E-NTPDase) 的 2 型酶。 E-NTPDases 是水解 5'-三磷酸的胞外核苷酶家族。这种 ecto-ATPase 是一种完整的膜蛋白。该基因的可变剪接导致多个转录变体。[RefSeq 提供，2008 年 7 月]

The protein encoded by this gene is the type 2 Enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]

ENTPD2 基因产物(2)

mRNA Protein Name
NM_001246.4 NP_001237.1 ectonucleoside triphosphate diphosphohydrolase 2 isoform 2
NM_203468.3 NP_982293.1 ectonucleoside triphosphate diphosphohydrolase 2 isoform 1
基因本体论
  • 分子功能
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
32814053 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

ENTPD2 蛋白结构

GDA1_CD39

GDA1_CD39: GDA1/CD39 (nucleoside phosphatase) family (35 - 450)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 495 a.a.
蛋白主名 其他名称

ectonucleoside triphosphate diphosphohydrolase 2

CD39 antigen-like 1

ENTPD2 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
ENTPD2 Q9Y5L3 OPTN Homo sapiens Q96CV9
Y2H Array
32814053
种属内
ENTPD2 Q9Y5L3 OPTN Homo sapiens Q96CV9
Y2H Pooling
32814053
种属内
ENTPD2 Q9Y5L3 OPTN Homo sapiens Q96CV9
Validated Y2H
32814053
种属间: 跨种属相互作用 种属内: 同种属相互作用

重组 ENTPD2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P72730 CD39L1/ENTPD2 Protein, Human (HEK293, His) Q9Y5L3 (T29-D460) ≥95%
HY-P76903 CD39L1/ENTPD2 Protein, Human (sf9, His) Q9Y5L3 (T29-D460) ≥95%

关联疾病

疾病名称 别名
Cholera

Vibrio Cholerae Infection

Cholera - Vibrio Cholerae

Cholera Due To Vibrio Cholerae

Vibrio Cholerae

Cholera Syndrome

Asiatic Cholera

Epidemic Cholera
Jejunoileitis
Megalencephalic Leukoencephalopathy With Subcortical Cysts 1

Van Der Knaap Disease

Leukoencephalopathy With Swelling And Cysts

MLC1

Vacuolating Megalencephalic Leukoencephalopathy With Subcortical Cysts

Lvm

Vl

Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, 1

Leukoencephalopathy, Megalencephalic, With Subcortical Cysts, Type 1

Megalencephalic Leukoencephalopathy With Subcortical Cysts
Palmoplantar Keratoderma And Congenital Alopecia 1

Autosomal Dominant Palmoplantar Keratoderma And Congenital Alopecia

PPKCA1

Keratoderma-Hypotrichosis-Leukonychia Totalis Syndrome

Autosomal Dominant Palmoplantar Hyperkeratosis And Congenital Alopecia

Palmoplantar Keratoderma And Congenital Alopecia, Stevanovic Type

Ppk-Ca, Stevanovic Type

Ppkca, Stevanovic Type

Palmoplantar Keratoderma With Congenital Alopecia

Ppkca Stevanovic Type

Alopecia Congenita With Hyperkeratosis Of The Palms And Soles

Alopecia Congenita Keratosis Palmoplantaris

Keratoderma, Palmoplantar, With Congenital Alopecia, Type 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS04396 ENTPD2 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus ENTPD2 RGD RGD:69266
Bos taurus ENTPD2 VGNC VGNC:28509
Mus musculus ENTPD2 MGD MGI:1096863
Felis catus ENTPD2 VGNC VGNC:61879
Macaca mulatta ENTPD2 VGNC VGNC:72225
Canis familiaris ENTPD2 VGNC VGNC:40381
Others ENTPD2 NCBI
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