GNA14 - G protein subunit alpha 14 Gene

中文名称：G 蛋白亚基α14

种属: Homo sapiens

同用名: HG1I

基因 ID: 9630 | 基因类型: protein coding

关于 GNA14

Cytogenetic location: 9q21.2 Genomic coordinates (GRCh38): 9:77,423,079-77,648,322 (from NCBI)

This gene has 2 transcripts (splice variants), 244 orthologues, 15 paralogues and is associated with 3 phenotypes. Broad expression in thyroid (RPKM 10.6), endometrium (RPKM 6.0) and 22 other tissues.

功能概要

该基因编码鸟嘌呤核苷酸结合或 G 蛋白家族的成员。 G 蛋白是由α、β 和γ 亚基组成的异源三聚体。编码的蛋白质是 G 蛋白 alpha 家族的成员，更具体地说是 G 蛋白的 alpha q 亚家族。编码的蛋白质可能在磷脂酶 C-β 及其下游效应子的百日咳毒素抗性激活中发挥作用。[RefSeq 提供，2009 年 2 月]

This gene encodes a member of the guanine nucleotide-binding, or G protein family. G proteins are heterotrimers consisting of alpha, beta and gamma subunits. The encoded protein is a member of the alpha family of G proteins, more specifically the alpha q subfamily of G proteins. The encoded protein may play a role in pertussis-toxin resistant activation of Phospholipase C-beta and its downstream effectors.[provided by RefSeq, Feb 2009]

GNA14 基因产物(1)

mRNA	Protein	Name
NM_004297.4	NP_004288.1	guanine nucleotide-binding protein subunit alpha-14

基因本体论

分子功能

分子功能 GO 注释	逻辑证据	参考文献	来源
enables protein binding	IPI IPI: 通过物理相互作用推断	25416956	GOA

EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

GNA14 蛋白结构

G-alpha

0
100
200
300
355 a.a.

蛋白主名

其他名称

guanine nucleotide-binding protein subunit alpha-14

g alpha-14

GNA14 蛋白互作信息

分类	蛋白名称	蛋白编号	互作蛋白	互作蛋白种属	互作蛋白编号	实验方法	参考文献
种属内	GNA14	O95837	DNAL4	Homo sapiens	O96015	Y2H Prey Pooling	25416956
种属内	GNA14	O95837	SETDB1	Homo sapiens	Q15047-2	Validated Y2H	32814053
种属内	GNA14	O95837	SETDB1	Homo sapiens	Q15047-2	Y2H Array	32814053
种属内	GNA14	O95837	SETDB1	Homo sapiens	Q15047-2	Y2H Pooling	32814053

种属间: 跨种属相互作用 种属内: 同种属相互作用

关联疾病

疾病名称

别名

Kaposiform Hemangioendothelioma

Congenital Cutaneous Multifocal Kaposiform Hemangioendothelioma	Kh
Khe	Kaposiform Hemangio-Endothelioma

Angioma, Tufted

Tufted Angioma	Angioma Tufted
Nakagawa Angioblastoma	Tufted Angioma Of Skin

Pyogenic Granuloma

Lobular Capillary Hemangioma	Granuloma Pyogenic
Granuloma Pyogenicum	Granuloma Telangiectaticum Of Skin
Pyogenic Granuloma Of Skin	Lobular Capillary Haemangioma Of Skin

Pertussis

Whooping Cough	Bordetella Infections
Bordetella Infection	Bordetella Pertussis Infection
Wc - Whooping Cough	Whooping Cough Due To Unspecified Organism
Bordetellosis	Tussis Convulsiva
Whooping Cough, Unspecified Organism	Wc - [Whooping Cough]
Whooping Cough Due To B. Parapertussis	Infection Due To Bordetella Parapertussis

Rapidly Involuting Congenital Hemangioma

Rich

Hyperinsulinemic Hypoglycemia, Familial, 5

Hyperinsulinism Due To Insr Deficiency	HHF5
Familial Hyperinsulinemic Hypoglycemia 5	Hyperinsulinemic Hypoglycemia Due To Insr Deficiency
Hyperinsulinemic Hypoglycemia Due To Insulin Receptor Deficiency	Congenital Hyperinsulinism
Persistent Hyperinsulinemic Hypoglycemia Of Infancy	Phhi
Hyperinsulinemic Hypoglycemia Familial 5

Spindle Cell Hemangioma

Sch	Spindle Cell Hemangioendothelioma

Sturge-Weber Syndrome

SWS	Encephalotrigeminal Angiomatosis
Encephalofacial Angiomatosis	Sturge-Weber-Dimitri Syndrome
Sturge-Weber-Krabbe Syndrome	Fourth Phacomatosis
Leptomeningeal Angiomatosis	Meningeal Capillary Angiomatosis
Sturge-Weber-Krabbe Angiomatosis	Sturge-Weber Syndrome, Somatic, Mosaic
Sws Type I - Facial And Leptomeningeal Angiomas	Sws Type Ii - Facial Angioma Alone, No Cns Involvement
Sws Type Iii - Isolated Leptomeningeal Angiomas	Sturge Weber Syndrome
Angiomatosis Aculoorbital-Thalamic Syndrome	Encephalofacial Hemangiomatosis
Encephalofacial Hemangiomatosis Syndrome	Meningo-Oculo-Facial Angiomatosis
Meningofacial Angiomatosis-Cerebral Calcification Syndrome	Neuroretinoangiomatosis
Phakomatosis, Sturge-Weber	Weber-Sturge-Dimitri Syndrome

Hemangioma

Hemangiomas

Multiple Enchondromatosis, Maffucci Type

Maffucci Syndrome	Chondrodysplasia With Hemangioma
Chondroplasia Angiomatosis	Enchondromatosis With Hemangiomata
Hemangiomatosis Chondrodystrophica	Kast Syndrome
Multiple Angiomas And Endochondromas	Dyschondrodysplasia With Hemangiomas
Enchondromatosis Type Ii	Enchondromatosis With Multiple Cavernous Hemangiomas
Dyschondroplasia And Cavernous Hemangioma	Hemangiomata With Dyschondroplasia

Capillary Hemangioma

Infantile Hemangioma	Strawberry Nevus Of Skin
Cellular Hemangioma Of Infancy	Congenital Vascular Hamartoma
Congenital Vascular Naevus	Juvenile Hemangioma
Strawberry Haemangioma	Strawberry Nevus
Hemangioma Capillary	Hemangioma, Capillary
Hemangioma, Cavernous

Klippel-Trenaunay-Weber Syndrome

Klippel-Trenaunay Syndrome	KTS
Ktw Syndrome	Angioosteohypertrophy Syndrome
Angio-Osteohypertrophy Syndrome	Klippel Trenaunay Syndrome
Klippel-Trénaunay-Weber Syndrome	Haemangiectatic Hypertrophy
Weber-Klippel-Trenaunay	Congenital Dysplastic Angiopathy
Klippel-Trenaunay Disease	Weber Klippel Trenaunay

Proteus Syndrome

Proteus Syndrome, Somatic	Partial Gigantism-Nevi-Hemihypertrophy-Macrocephaly Syndrome
Gigantism, Partial, Of Hands And Feet, Nevi, Hemihypertrophy, And Macrocephaly	Wiedemann'S Syndrome
Hemihypertrophy And Macrocephaly	Partial Gigantism Of Hands And Feet, Nevi, Hemihypertrophy, Macrocephaly
Ps	PROTEUSS
Partial Gigantism Of Hands And Feet Nevi Hemihypertrophy And Macrocephaly

Cavernous Hemangioma

Hemangioma, Cavernous	Cavernoma
Cavernous Haemangioma

疾病名称	别名
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-RS05532	GNA14 Human Pre-designed siRNA Set A	Pre-designed Sets	/	否

直系同源

种属	基因名	来源	基因 ID
Felis catus	GNA14	VGNC	VGNC:102934
Macaca mulatta	GNA14	VGNC	VGNC:73088
Canis familiaris	GNA14	VGNC	VGNC:41299
Bos taurus	GNA14	VGNC	VGNC:29447
Mus musculus	GNA14	MGD	MGI:95769
Rattus norvegicus	GNA14	RGD	RGD:1308122
Others	GNA14	NCBI

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MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。

站点地图隐私声明

沪ICP备15051369号-4

上海工商

沪公网安备31011502019417

沪(浦)应急管危经许[2021]201709(QFYS)

营业执照（三证合一）

GNA14 - G protein subunit alpha 14 Gene

关于 GNA14

功能概要

GNA14 基因产物(1)

GNA14 蛋白结构

GNA14 蛋白互作信息

关联疾病

直系同源

热门区域

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GNA14 - G protein subunit alpha 14 Gene

关于 GNA14

功能概要

GNA14 基因产物(1)

GNA14 蛋白结构

GNA14 蛋白互作信息

关联疾病

相关产品

直系同源

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z