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  2. RAB11FIP3 - RAB11 family interacting protein 3 Gene

RAB11FIP3 - RAB11 family interacting protein 3 Gene

中文名称:RAB11 家族相互作用蛋白 3

种属: Homo sapiens

同用名: CART1; FIP3-Rab11; Rab11-FIP3

基因 ID: 9727 | 基因类型: protein coding

关于 RAB11FIP3

Cytogenetic location: 16p13.3 Genomic coordinates (GRCh38): 16:425,649-523,011 (from NCBI)

This gene has 11 transcripts (splice variants), 1 gene allele, 204 orthologues and 1 paralogue. Broad expression in kidney (RPKM 33.4), brain (RPKM 8.0) and 25 other tissues.

功能概要

大型 Rab GTPase 家族的蛋白质 (参见 RAB1A;MIM 179508) 在细胞内运输囊泡的形成、靶向和融合中具有调节作用。 RAB11FIP3 是许多与 Rab GTP 酶相互作用并对其进行调节的蛋白质之一 (Hales 等人,2001 [PubMed 11495908]) 。[OMIM 提供,2008 年 3 月]

Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]

RAB11FIP3 基因产物(3)

mRNA Protein Name
NM_001142272.2 NP_001135744.2 rab11 family-interacting protein 3 isoform 2
NM_001370401.1 NP_001357330.1 rab11 family-interacting protein 3 isoform 3
NM_014700.4 NP_055515.1 rab11 family-interacting protein 3 isoform 1

RAB11FIP3 蛋白结构

EF-hand_7

EF-hand_7: EF-hand domain pair (206 - 262)

RBD-FIP

RBD-FIP: FIP domain (716 - 756)

  • 0
  • 200
  • 400
  • 600
  • 756 a.a.
蛋白主名 其他名称

rab11 family-interacting protein 3

EF hands-containing Rab-interacting protein

关联疾病

疾病名称 别名
Congenital Muscular Dystrophy-Dystroglycanopathy A7

Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies Type A7

Mddga7

Walker-Warburg Syndrome Or Muscle-Eye-Brain Disease Ispd-Related

Congenital Muscular Dystrophy-Dystroglycanopathy With Brain And Eye Anomalies, Type A7

Large Cell Medulloblastoma
Breast Cancer

Breast Carcinoma

Male Breast Cancer

Breast Cancer, Familial

Malignant Neoplasm Of Breast

Breast Cancer, Susceptibility To

Breast Cancer, Early-Onset

Malignant Tumor Of Breast

Carcinoma Of Male Breast

Breast Cancer, Invasive Ductal

Breast Cancer, Protection Against

Breast Cancer, Somatic

Breast Cancer, Male

Breast Cancer, Lobular, Somatic

Breast Tumor

Mammary Cancer

Mammary Tumor

Malignant Neoplasm Of Male Breast

Mammary Carcinoma

Male Breast Carcinoma

Familial Cancer Of Breast

Invasive Ductal Breast Carcinoma

Breast Cancer Susceptibility

Breast Cancer, Male, Susceptibility To

Breast Cancer, Early-Onset, Susceptibility To

Malignant Tumor Of The Breast

Mammary Neoplasm

Primary Breast Cancer

Neoplasm Of Male Breast

Carcinoma Of Breast

Breast Cancer In Men

Familial Breast Cancer

Cancer Of Breast

BC

Breast Cancer Familial

Breast Cancer Familial Male

Breast Cancer, Familial Male

Breast Male Carcinoma

Breast Neoplasms

Breast Neoplasms, Male

Mammary Tumors

Mammary Carcinomas

Cancer, Breast

Cancer, Breast, Susceptibility

Invasive Breast Ductal Carcinoma

Breast Neoplasm

Susceptibility To Breast Cancer

Mammary Neoplasms

Animal Mammary Neoplasms

Primary Malignant Neoplasm Of Breast

Infiltrating Ductal Carcinoma Of Breast

Infiltrating Duct Carcinoma Of Unspecified Site

Infiltrating Ductular Carcinoma Of Unspecified Site

Invasive Breast Carcinoma Of No Special Type

Microinvasive Carcinoma Of Breast

Carcinoma With Apocrine Differentiation

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus RAB11FIP3 RGD RGD:1308952
Bos taurus RAB11FIP3 VGNC VGNC:33618
Macaca mulatta RAB11FIP3 VGNC VGNC:76500
Mus musculus RAB11FIP3 MGD MGI:2444431
Felis catus RAB11FIP3 VGNC VGNC:64469