2. Gene
  3. URB1 - URB1 ribosome biogenesis homolog Gene

URB1 - URB1 ribosome biogenesis homolog Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：URB1 核糖体生物合成同系物

种属: Homo sapiens

同用名: NPA1; C21orf108

基因 ID: 9875 | 基因类型: protein coding

关于 URB1

Cytogenetic location: 21q22.11 Genomic coordinates (GRCh38): 21:32,311,018-32,393,012 (from NCBI)

This gene has 3 transcripts (splice variants) and 196 orthologues. Ubiquitous expression in testis (RPKM 5.5), endometrium (RPKM 5.1) and 25 other tissues.

功能概要

启用 RNA 结合活性。预计参与来自三顺反子 rRNA 转录物 (SSU-rRNA、5.8S rRNA、LSU-rRNA) 的 5.8S rRNA 的成熟和来自三顺反子 rRNA 转录物的 LSU-rRNA 的成熟 (SSU-rRNA、5.8S rRNA、LSU-rRNA) .位于纤维中心。 [由基因组资源联盟提供，2022 年 4 月]

Enables RNA binding activity. Predicted to be involved in maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) and maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Located in fibrillar center. [provided by Alliance of Genome Resources, Apr 2022]

URB1 基因产物(1)

mRNA Protein Name
NM_014825.3 NP_055640.2 nucleolar pre-ribosomal-associated protein 1
基因本体论
  • 细胞组分
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in nucleolus IDA
IDA: 通过直接分析推断
16963496 GOA
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断

URB1 蛋白结构

Npa1

Npa1: Ribosome 60S biogenesis N-terminal (74 - 394)

  • 0
  • 400
  • 800
  • 1200
  • 1600
  • 2000
  • 2271 a.a.
蛋白主名 其他名称

nucleolar pre-ribosomal-associated protein 1

URB1 ribosome biogenesis 1 homolog

关联疾病

疾病名称 别名
Tick Paralysis
X-Linked Intellectual Disability-Short Stature-Overweight Syndrome

Mrx12

Mrx35

X-Linked Mental Retardation 12

X-Linked Mental Retardation 35
Niemann-Pick Disease, Type B

Niemann-Pick Disease Type B

Acid Sphingomyelinase Deficiency, Visceral Type

Asmd, Visceral Type

Niemann Pick Disease Type B

Chronic Visceral Acid Sphingomyelinase Deficiency

Chronic Visceral Asmd

Npd-B

Niemann-Pick Disease B

NPDB

Niemann-Pick Disease Adult Non-Neuronopathic Form

Niemann-Pick Disease Intermediate With Visceral Involvement And Rapid Progression

Niemann-Pick Disease Type E

Niemann-Pick Disease Type F

Niemann-Pick Disease Type I

Niemann-Pick Disease Visceral Form

Npb

Sphingomyelinase Deficiency

Sphingomyelin Lipidosis

Niemann-Picks Disease Type B

Niemann-Pick Disease, Type E

Niemann-Pick Diseases

Niemann-Pick Disease, Type A
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS15505 URB1 Human Pre-designed siRNA Set A Pre-designed Sets / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus URB1 RGD RGD:1304621
Canis familiaris URB1 VGNC VGNC:53050
Macaca mulatta URB1 VGNC VGNC:79074
Felis catus URB1 VGNC VGNC:66851
Bos taurus URB1 VGNC VGNC:53611
Mus musculus URB1 MGD MGI:2146468
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