1. Immunology/Inflammation
  2. CD47
  3. Gentulizumab

Gentulizumab  (Synonyms: Gensci-059)

目录号: HY-P991062
技术支持

Gentulizumab (Gensci-059) 是一种人源化 IgG4 抗体,靶向结合 CD47。Gentulizumab 在人类和猴子中均表现出与 CD47 的强结合,并有效抑制 CD47-SIRPα 相互作用。Gentulizumab 表现出强效的抗肿瘤活性。Gentulizumab 的同型对照可参考 Human IgG4 (S228P) kappa, Isotype Control (HY-P99003)。

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Gentulizumab Chemical Structure

Gentulizumab Chemical Structure

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     可免费申领三个不同产品的试用装。

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gentulizumab (Gensci-059) is a humanized IgG4 antibody that targets CD47. Gentulizumab displays strong binding to CD47 in both human and monkey, and effectively inhibits the CD47-SIRPα interaction. Gentulizumab exhibits a potent antitumor activity. The isotype control for Gentulizumab can refer to Human IgG4 (S228P) kappa, Isotype Control (HY-P99003)[1].

中文名称

金妥利珠单抗

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Gentulizumab
目录号:
HY-P991062
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