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  3. 疾病研究领域 植物 其他类 硫苷
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  6. Gigantol

Gigantol 是一种天然产物，可从 Cymbidium giganteum 中分离得到。Gigantol 是豚鼠回肠自发收缩的有效抑制剂。

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Gigantol Chemical Structure

Gigantol Chemical Structure

CAS No. : 83088-28-2

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规格 价格 是否有货 数量
10 mM * 1 mL in DMSO ￥3138
In-stock
1 mg ￥1040
In-stock
5 mg ￥2200
In-stock
10 mg ￥3500
In-stock
50 mg   询价  
100 mg   询价  

* Please select Quantity before adding items.

Customer Review

Gigantol 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Gigantol is a natural product that could be isolated from Cymbidium giganteum. Gigantol is a potent inhibitor of the spontaneous contractions of the guinea-pig ileum[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
A549 IC50
> 10 μM
Compound: 17
Cytotoxicity against human A549 cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human A549 cells assessed as decrease in cell viability after 6 days by MTT assay
[PMID: 27310249]
HCCLM3 IC50
57.9 μM
Compound: 27
Antiproliferative activity against human HCCLM3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HCCLM3 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
[PMID: 34931827]
HeLa IC50
> 10 μM
Compound: 17
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human HeLa cells assessed as decrease in cell viability after 6 days by MTT assay
[PMID: 27310249]
HepG2 IC50
1.883 μM
Compound: 27
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
Antiproliferative activity against human HepG2 cells assessed as inhibition of cell growth measured after 48 hrs by MTT assay
[PMID: 34931827]
MCF7 IC50
> 10 μM
Compound: 17
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 6 days by MTT assay
Cytotoxicity against human MCF7 cells assessed as decrease in cell viability after 6 days by MTT assay
[PMID: 27310249]
NCI-H460 IC50
247.55 μM
Compound: 1
Cytotoxicity against human NCI-H460 cells assessed as cell viability for 24 hrs by MTT assay
Cytotoxicity against human NCI-H460 cells assessed as cell viability for 24 hrs by MTT assay
[PMID: 24844664]
Neutrophil IC50
2.1 μM
Compound: 33
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
Antiinflammatory activity in human neutrophils assessed as inhibition of FMLP/cytochalasin B-induced superoxide anion generation by measuring superoxide dismutase-inhibitable reduction of ferricytochrome c preincubated for 5 mins followed by FMLP/cytochal
[PMID: 27525452]
Neutrophil IC50
3.2 μM
Compound: 33
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
Antiinflammatory activity in human neutrophils assessed as inhibition of fMLP/CB-induced elastase release using MeO-Suc-Ala-Ala-Pro-Val-p-nitroanilide as elastase substrate preincubated for 5 mins followed by fMLP/CB-induction
[PMID: 27525452]
分子量

274.31

Formula

C16H18O4
CAS 号
性状

油状物

颜色

Colorless to light yellow

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Pure form -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 50 mg/mL (182.28 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.6455 mL 18.2276 mL 36.4551 mL
5 mM 0.7291 mL 3.6455 mL 7.2910 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.79%

COA (167 KB) LCMS (259 KB)

产品使用指南 (1538 KB)
参考文献

Gigantol 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.6455 mL 18.2276 mL 36.4551 mL 91.1378 mL
5 mM 0.7291 mL 3.6455 mL 7.2910 mL 18.2276 mL
10 mM 0.3646 mL 1.8228 mL 3.6455 mL 9.1138 mL
15 mM 0.2430 mL 1.2152 mL 2.4303 mL 6.0759 mL
20 mM 0.1823 mL 0.9114 mL 1.8228 mL 4.5569 mL
25 mM 0.1458 mL 0.7291 mL 1.4582 mL 3.6455 mL
30 mM 0.1215 mL 0.6076 mL 1.2152 mL 3.0379 mL
40 mM 0.0911 mL 0.4557 mL 0.9114 mL 2.2784 mL
50 mM 0.0729 mL 0.3646 mL 0.7291 mL 1.8228 mL
60 mM 0.0608 mL 0.3038 mL 0.6076 mL 1.5190 mL
80 mM 0.0456 mL 0.2278 mL 0.4557 mL 1.1392 mL
100 mM 0.0365 mL 0.1823 mL 0.3646 mL 0.9114 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Gigantol83088-28-2Othersnatural productCymbidium giganteumguinea-pig ileumInhibitorinhibitorinhibit

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