2. Anti-infection Metabolic Enzyme/Protease
  3. Bacterial Fungal Cytochrome P450
  4. GlcN-6-P Synthase-IN-1

GlcN-6-P Synthase-IN-1 (Compound 4d) 是一种氨基葡萄糖-6-磷酸合成酶（GlcN-6-P synthase）抑制剂，IC50 为 3.47 μM。GlcN-6-P Synthase-IN-1 具有显著的抗菌（antimicrobial）活性。GlcN-6-P Synthase-IN-1 在 CNS 中具有良好的穿透性，能抑制 cytochrome P450 CYP3A4 异构体。

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GlcN-6-P Synthase-IN-1 Chemical Structure

GlcN-6-P Synthase-IN-1 Chemical Structure

CAS No. : 2447602-44-8

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GlcN-6-P Synthase-IN-1 相关抗体

Top Publications Citing Use of Products

查看 Cytochrome P450 亚型特异性产品:

查看所有亚型
CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GlcN-6-P Synthase-IN-1 (Compound 4d) is a Glucosamine-6-phosphate (GlcN-6-P) synthase inhibitor with an IC50 of 3.47 μM. GlcN-6-P Synthase-IN-1 exhibits significant antimicrobial activity. GlcN-6-P Synthase-IN-1 has good penetration in the CNS and is able to inhibit the cytochrome P450, CYP3A4 isoform[1].

IC50 & Target

IC50: 3.47 μM (GlcN-6-P synthase)[1]
体外研究
(In Vitro)

GlcN-6-P Synthase-IN-1 (Compound 4d) shows antimicrobial activity with MIC values of 1 ± 0.15, 0.5 ± 0.15, 4 ± 0.33 and 4 ± 0.33 µg/mL against S. aureus, B. subtilis, C. albicans and A. oryzae, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

GlcN-6-P Synthase-IN-1 相关抗体:
分子量

391.49

Formula

C20H21N7S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GlcN-6-P Synthase-IN-1 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GlcN-6-P Synthase-IN-12447602-44-8BacterialFungalCytochrome P450CYPsS. aureusB. subtilisC. albicansA. oryzaeantimicrobialCNS penetrationInhibitorinhibitorinhibit

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