Glycopyrrolate-d₃ bromide  (Synonyms: 格隆溴铵-d₃; Glycopyrronium-d₃ bromide)

Glycopyrrolate-d₃ (bromide) is deuterium labeled Glycopyrrolate. Glycopyrrolate (Glycopyrronium bromide), a quaternary ammonium derivative, is a muscarinic receptor antagonist. Glycopyrrolate has bronchoprotective effect and produces a beneficial effect on blood pressure. Glycopyrrolate can be used for the research of bronchial diseases^[1][2][3][4].

401.35

C₁₉H₂₅D₃BrNO₃

596-51-0

格隆溴铵-d₃；甘罗溴铵-d₃

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. Maarsingh H, et al. Effects of (a Combination of) the Beta2-Adrenoceptor Agonist Indacaterol and the Muscarinic Receptor Antagonist Glycopyrrolate on Intrapulmonary Airway Constriction [J]. Cells, 2021, 10(5): 1237.  [Content Brief]

  [3]. Dyson D H, et al. Dose effect and benefits of glycopyrrolate in the treatment of bradycardia in anesthetized dogs [J]. The Canadian Veterinary Journal, 1999, 40(5): 327.  [Content Brief]

  [4]. Hansel T T, Neighbour H, Erin E M, et al. Glycopyrrolate causes prolonged bronchoprotection and bronchodilatation in patients with asthma [J]. Chest, 2005, 128(4): 1974-1979.  [Content Brief]