1. Cell Cycle/DNA Damage Stem Cell/Wnt Cytoskeleton TGF-beta/Smad Epigenetics Neuronal Signaling
  2. ROCK Aurora Kinase CaMK
  3. Glycyl H-1152 hydrochloride

Glycyl H-1152 hydrochloride 是 Rho-kinase 抑制剂 H-1152 dihydrochloride 的糖基衍生物。Glycyl H-1152 hydrochloride 抑制 ROCKIIAurora ACAMKIIPKGIC50 值分别为 0.0118、2.35、2.57 和 3.26 μM。Glycyl H-1152 hydrochloride 比 H-1152 dihydrochloride 具有更高的选择性。

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Glycyl H-1152 hydrochloride Chemical Structure

Glycyl H-1152 hydrochloride Chemical Structure

CAS No. : 913844-45-8

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规格 价格 是否有货 数量
500 μg ¥1962
3 - 4 周

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Other Forms of Glycyl H-1152 hydrochloride:

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Glycyl H-1152 hydrochloride (compound 18) is a glycyl derivative of Rho-kinase inhibitors H-1152 dihydrochloride. Glycyl H-1152 hydrochloride inhibits ROCKII, Aurora A, CAMKII and PKG, with IC50s of 0.0118, 2.35, 2.57 and 3.26 μM respectively. Glycyl H-1152 hydrochloride has higher selective than H-1152 hydrochloride[1].

IC50 & Target[1]

ROCKII

11.8 nM (IC50)

Aurora A

2.35 μM (IC50)

CaMK II

2.57 μM (IC50)

PKG

3.26 μM (IC50)

分子量

449.40

Formula

C18H26Cl2N4O3S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Glycyl H-1152 hydrochloride
目录号:
HY-15720B
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