2. Apoptosis Protein Tyrosine Kinase/RTK
  3. Discoidin Domain Receptor c-Kit PDGFR c-Myc
  4. GW694590A

GW694590A  (Synonyms: UNC10112731)

目录号: HY-160689
产品使用指南

摩尔计算器

GW694590A (UNC10112731) 是 MYC 蛋白稳定剂，能够增加内源性 MYC 蛋白的水平。GW694590A 还靶向受体酪氨酸激酶，在 1 μM 时，对 DDR2、KIT 和 PDGFRα 的抑制率分别为 81%、68% 和 67%。GW694590A 是跨 ATP 依赖性和非依赖性荧光素酶的蛋白激酶抑制剂，对 Fluc 报告基因有潜在影响。

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GW694590A Chemical Structure

GW694590A Chemical Structure

CAS No. : 948313-24-4

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GW694590A 相关抗体

Top Publications Citing Use of Products

查看 Discoidin Domain Receptor 亚型特异性产品:

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DDR1 DDR2

查看 PDGFR 亚型特异性产品:

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PDGFR PDGFRβ PDGFRα

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

GW694590A (UNC10112731) is a MYC protein stabilizer that increases endogenous MYC protein levels. GW694590A also targets receptor tyrosine kinases, inhibiting DDR2, KIT and PDGFRα by 81% at 1 μM. , 68% and 67%. GW694590A is a protein kinase inhibitor across ATP-dependent and -independent luciferases with potential effects on the Fluc reporter gene[1].

分子量

417.42

Formula

C22H19N5O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

GW694590A 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

GW694590A948313-24-4UNC10112731UNC 10112731UNC-10112731Discoidin Domain Receptorc-KitPDGFRc-MycSCFRCD117Platelet-derived growth factor receptorMycInhibitorinhibitorinhibit

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