2. Cytoskeleton TGF-beta/Smad Stem Cell/Wnt Epigenetics Cell Cycle/DNA Damage
  3. Myosin PKA PKC ROCK
  4. HA-100 dihydrochloride

HA-100 dihydrochloride 是一种有效的蛋白激酶抑制剂，抑制 PKG，PKA，PKC 和 MLC 激酶的 IC50 值分别为 4 μM、8 μM、12 μM 和 240 μM。HA-100 dihydrochloride 也用作 ROCK 抑制剂。

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HA-100 dihydrochloride Chemical Structure

HA-100 dihydrochloride Chemical Structure

CAS No. : 210297-47-5

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HA-100 dihydrochloride 的其他形式现货产品:

Customer Review

Other Forms of HA-100 dihydrochloride:

HA-100 dihydrochloride 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

查看 PKA 亚型特异性产品:

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PKA PKAR

查看 PKC 亚型特异性产品:

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PKC PKCα PKCβ PKCγ PKCδ PKCε PKCη PKCζ PKCθ PKCμ PKCι

查看 ROCK 亚型特异性产品:

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ROCK ROCK1 ROCK2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HA-100 dihydrochloride is a potent protein kinase inhibitor, with IC50s of 4 μM, 8 μM, 12 μM and 240 μM for cGMP-dependent protein kinase (PKG), cAMP-dependent protein kinase (PKA), protein kinase C (PKC) and MLC-kinase, respectively. HA-100 dihydrochloride also used as a ROCK inhibitor[1][2].

IC50 & Target[1]

PKA

8 μM (IC50)

PKC

12 μM (IC50)

PKC

6.5 μM (Ki)

PKG

4 μM (IC50)

MLCK

240 μM (IC50)

MLCK

61 μM (Ki)

体外研究
(In Vitro)

HA-100 dihydrochloride 是 ATP 竞争性的抑制 MLC 激酶和 PKC，Ki 值分别为 61 和 6.5 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HA-100 dihydrochloride 相关抗体:
分子量

350.26

Formula

C13H17Cl2N3O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HA-100 dihydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HA-100210297-47-5HA100HA 100MyosinPKAPKCROCKProtein kinase AProtein kinase CRho-associated protein kinaseRho-associated kinaseRho-kinaseROKInhibitorinhibitorinhibit

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产品名称：
HA-100 dihydrochloride
目录号：
HY-12880
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