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  4. Halofenozide

Halofenozide  (Synonyms: 氯虫酰肼; RH-0345)

目录号: HY-113890 纯度: 99.42%
COA 产品使用指南 技术支持

Halofenozide (RH-0345) 是一种蜕皮激素 (ecdysteroid) 激动剂。 RH-0345 属于一组新的昆虫生长调节剂 (IGR)，具有苯甲酰肼结构，可模拟天然昆虫蜕皮激素 20-羟基蜕皮激素的作用。

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Halofenozide Chemical Structure

Halofenozide Chemical Structure

CAS No. : 112226-61-6

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规格 价格 是否有货 数量
Free Sample (0.1 - 0.2 mg)   Apply now  
10 mM * 1 mL in DMSO ￥655
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1 mg ￥500
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5 mg ￥900
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10 mg ￥1200
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25 mg ￥2100
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50 mg ￥3100
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100 mg ￥4340
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500 mg 现货 询价
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Customer Review

Halofenozide 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Halofenozide (RH-0345) is an ecdysteroid agonist. RH-0345 belongs to a new group of insect growth regulators (IGRs) with a benzoylhydrazine structure that mimic the action of the natural insect molting hormone 20-hydroxyecdysone[1].

体外研究
(In Vitro)

Halofenozide (RH-0345) reduces both growth and development of oocytes in vitro[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Halofenozide 相关抗体:

Cell Viability Assay[2]

Cell Line: Cultured ovaries were dissected from female adult beetles of mealworm, Tenebrio molitor (T. molitor)
Concentration: 1 μM and 10 μM
Incubation Time: 4 days
Result: Did not cause a significant effect on ecdysteroid amounts in the culture medium using ovaries from 0- and 2-day-old females at 10 μM.
Caused a small significant increase of the amounts of ovarian ecdysteroids in the culture medium at 1 μM in the culture medium and with 2-day-old ovaries.
体内研究
(In Vivo)

After topical application of Halofenozide (RH-0345; 5 and 10 μg) on adult females, the highest dose (10 μg) reduces significantly the reproductive parameters scored: namely the oviposition period, the fecundity and the egg viability[1].
Halofenozide at the two doses tested (5 and 10 μg) causes smaller eggs with a decrease in length, width and volume[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Newly emerged (0-day-old) adult females of T. molitor [1]
Dosage: 5 and 10 μg
Administration: Topically applied
Result: Caused smaller eggs with a decrease in length, width and volume at the two doses tested (5 and 10 μg) .
分子量

330.81

Formula

C18H19ClN2O2
CAS 号
性状

固体

颜色

White to off-white

中文名称

氯虫酰肼
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验： 

DMSO 中的溶解度 : 125 mg/mL (377.86 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响，请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.0229 mL 15.1144 mL 30.2288 mL
5 mM 0.6046 mL 3.0229 mL 6.0458 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料

纯度: 99.42%

COA (284 KB) HNMR (257 KB) LCMS (96 KB)

产品使用指南 (1538 KB)
参考文献

Halofenozide 相关分类

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；一旦配成溶液，请分装保存，避免反复冻融造成的产品失效。
储备液的保存方式和期限：-80°C, 6 months; -20°C, 1 month。-80°C储存时，请在6个月内使用，-20°C储存时，请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.0229 mL 15.1144 mL 30.2288 mL 75.5721 mL
5 mM 0.6046 mL 3.0229 mL 6.0458 mL 15.1144 mL
10 mM 0.3023 mL 1.5114 mL 3.0229 mL 7.5572 mL
15 mM 0.2015 mL 1.0076 mL 2.0153 mL 5.0381 mL
20 mM 0.1511 mL 0.7557 mL 1.5114 mL 3.7786 mL
25 mM 0.1209 mL 0.6046 mL 1.2092 mL 3.0229 mL
30 mM 0.1008 mL 0.5038 mL 1.0076 mL 2.5191 mL
40 mM 0.0756 mL 0.3779 mL 0.7557 mL 1.8893 mL
50 mM 0.0605 mL 0.3023 mL 0.6046 mL 1.5114 mL
60 mM 0.0504 mL 0.2519 mL 0.5038 mL 1.2595 mL
80 mM 0.0378 mL 0.1889 mL 0.3779 mL 0.9447 mL
100 mM 0.0302 mL 0.1511 mL 0.3023 mL 0.7557 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Halofenozide112226-61-6RH-0345氯虫酰肼RH0345RH 0345Othersecdysteroidinsectgrowthregulatorhormone 20-hydroxyecdysoneecdysoneOvariesEcdysteroidsMealwormTenebriomolitorInhibitorinhibitorinhibit

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