1. 多肽产品
  2. 多肽及其衍生物
  3. 激素肽与神经肽
  4. Head activator neuropeptide

Head activator neuropeptide 是神经元或神经内分泌来源的哺乳动物细胞系的有丝分裂原。Head activator neuropeptide 通过结合 GPR37 进行信号传导,并刺激细胞进行有丝分裂。

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Custom Peptide Synthesis

Head activator neuropeptide Chemical Structure

Head activator neuropeptide Chemical Structure

CAS No. : 79943-68-3

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Head activator neuropeptide is a mitogen for mammalian cell lines of neuronal or neuroendocrine origin. Head activator neuropeptide signals by binding GPR37 and stimulates cells to enter mitosis[1].

IC50 & Target

GPR37[1]

体外研究
(In Vitro)

Head activator neuropeptide (2 nM,0-60 分钟) 在转染了 GPR37-FLAG 的 COS-7 细胞中刺激 GPR37 的内化[1]
Head activator neuropeptide (EC50: 3.3 nM) 增加转染载脂蛋白和 GPR37[1] 的 CHO-K1 细胞中的 Ca2+ mobilisation[1]
Head activator neuropeptide (EC50: 5.6 nM) 刺激表达 GPR37 的青蛙卵母细胞的电流增加[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1125.32

Formula

C54H84N12O14

CAS 号
Sequence Shortening

Glp-PPGGSKVILF

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Head activator neuropeptide
目录号:
HY-P3840
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