2. JAK/STAT Signaling Protein Tyrosine Kinase/RTK Membrane Transporter/Ion Channel
  3. EGFR Potassium Channel
  4. HER2-IN-13

HER2-IN-13 (Compound 33) 是一种 HER2 抑制剂，其 IC50 为 8 nM。HER2-IN-13 还能抑制 wt-EGFR，其 IC50 为 0.40 μM。

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HER2-IN-13 Chemical Structure

HER2-IN-13 Chemical Structure

CAS No. : 2414056-34-9

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Other Forms of HER2-IN-13:

HER2-IN-13 相关抗体

Top Publications Citing Use of Products

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EGFR/ErbB1/HER1 ErbB2/HER2 ErbB3/HER3 ErbB4/HER4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

HER2-IN-13 (Compound 33) is an HER2 inhibitor with an IC50 of 8 nM. HER2-IN-13 also inhibits wt-EGFR with an IC50 of 0.40 μM[1].

IC50 & Target[1]

HER2

8 nM (IC50)

EGFR (WT)

0.40 μM (IC50)

hERG

13.3 μM (IC50)

体外研究
(In Vitro)

HER2-IN-13 (Compound 33) 抑制 hERG 通道，IC50 为 13.3 μM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

HER2-IN-13 相关抗体:
分子量

568.96

Formula

C26H23ClF2N8O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

HER2-IN-13 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

HER2-IN-132414056-34-9EGFRPotassium ChannelEpidermal growth factor receptorErbB-1HER1KcsAInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-153557
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